Course Schedule - Spring Semester 2021

     

BIOE 515 901 (CRN: 24200)

ENGINEERING DRUG DELIVERY SYS.

Long Title: ENGINEERING DRUG DELIVERY SYSTEMS
Department: Bioengineering
Instructor: McHugh, Kevin J.
Meeting: 1:30PM - 2:50PM TR FULLY ONLINE (25-JAN-2021 - 30-APR-2021) 
Session: Full Term
Grade Mode: Standard Letter
Course Type: Lecture
Language of Instruction: Taught in English
Method of Instruction: Online
Credit Hours: 3
Course Syllabus:
Course Materials: Rice Campus Store
 
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Section Max Enrollment: 15
Section Enrolled: 7
Enrollment data as of: 6-DEC-2021 9:30AM
 
Additional Fees: None
 
Final Exam: GR Course-Dept Schedules Exam
 
Description: This course will focus on the application of innovative engineering approaches to enhance drug efficacy and/or reduce toxicity. Topics of emphasis include, but are not limited to, routes of administration, bioavailability, biodistribution, pharmacokinetics, pharmacodynamics, therapeutic drug windows, patient compliance, immunogenicity, the foreign body reaction, and solubility enhancement. A wide array of device types will be discussed, such as biodegradable microspheres, self-assembled lipid nanoparticles, microneedles, and osmotic pumps. Students will be expected to quantitatively evaluate drug release from complex devices and determine drug distribution and clearance using multi-compartment models. An additional project will be required of graduate level students.