Course Schedule - Fall Semester 2019

     

BIOE 515 001 (CRN: 14445)

ENGINEERING DRUG DELIVERY SYS.

Long Title: ENGINEERING DRUG DELIVERY SYSTEMS
Department: Bioengineering
Instructor: McHugh, Kevin J.
Meeting: 1:00PM - 2:15PM TR BRC 284 (26-AUG-2019 - 6-DEC-2019) 
Session: Full Term
Grade Mode: Standard Letter
Course Type: Lecture
Method of Instruction: Face to Face
Credit Hours: 3
Course Syllabus:
Course Materials: Rice Campus Store
 
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Section Max Enrollment: 30
Section Enrolled: 12
Enrollment data as of: 28-SEP-2020 1:11PM
 
Fees: None
 
Final Exam: GR Course-Dept Schedules Exam
 
Description: This course will focus on the application of innovative engineering approaches to enhance drug efficacy and/or reduce toxicity. Topics of emphasis include, but are not limited to, routes of administration, bioavailability, biodistribution, pharmacokinetics, pharmacodynamics, therapeutic drug windows, patient compliance, immunogenicity, the foreign body reaction, and solubility enhancement. A wide array of device types will be discussed, such as biodegradable microspheres, self-assembled lipid nanoparticles, microneedles, and osmotic pumps. Students will be expected to quantitatively evaluate drug release from complex devices and determine drug distribution and clearance using multi-compartment models. An additional project will be required of graduate level students.