Course Schedule - Fall Semester 2019

     

SSPB 502 001 (CRN: 13805)

INTRO SYSTEMS BIOLOGY MODELING

Long Title: INTRO COMPUTATIONAL SYSTEMS BIOLOGY: MODELING & DESIGN PRINCIPLES OF BIOCHEM NETWORKS
Department: Systems/Synthetic/Phys Biology
Instructor: Igoshin, Oleg
Meeting: 10:50AM - 12:05PM TR BRC 285 (26-AUG-2019 - 6-DEC-2019) 
Session: Full Term
Grade Mode: Standard Letter
Course Type: Lecture
Language of Instruction: Taught in English
Method of Instruction: Face to Face
Credit Hours: 3
Course Syllabus:
Course Materials: Rice Campus Store
 
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Section Max Enrollment: 25
Section Enrolled: 17
Total Cross-list Max Enrollment: 50
Total Cross-list Enrolled: 25
Enrollment data as of: 21-APR-2021 9:26AM
 
Additional Fees: None
 
Final Exam: Scheduled Final Exam-OTR Room
Final Exam Time:
18-DEC-2019  
7:00PM - 10:00PM W BRC 286
 
Description: The course summarizes techniques for quantitative analysis and simulations of basic circuits in genetic regulation, signal transduction and metabolism. We discuss engineering approaches adapted to computational systems biology and aim to formulate evolutionary design principles explaining organization of networks in terms of their physiological demands. We discuss biochemical simulation methodology and software as well as recent advances in the field. Topics include end-product inhibition in biosynthesis, optimality and robustness of the signaling networks and kinetic proofreading. More emphasis on recent advances in the field - paper reading and presentations. Cross-list: BIOE 490, BIOE 552. Recommended Prerequisite(s): Basic knowledge of biochemistry, cell biology, linear algebra, and ordinary differential equations is expected.