Description: This seminar introduces pre- and postdoctoral students in biomedical informatics to topics relevant to professional development in the discipline, which is no longer concentrated in labs as it was in its early days, but is now important in hospitals, outpatient clinics, companies and even the community. In these settings, researchers and practitioners are likely to encounter not only difficult technical challenges, but vexing problems of organizational change and development as well. We will consider some of these challenges, drawing on the insights of experts in psychology, organizational change, management and communications along with industry representatives and entrepreneurs. The seminar mixes lectures and readings with group and individual exercises.