Description: This course presents the theoretical foundations of cellular and systems neuroscience from a quantitative perspective, integrating mathematical modeling, computational tools, and data analysis. Students will develop and apply differential equations, probabilistic models, and reverse correlation techniques to analyze neural activity and synaptic interactions. The course combines traditional lectures with student-led presentations in a seminar-style format. Coursework includes problem sets, coding-based assignments, and group projects. MATLAB or Python proficiency is strongly recommended. Cross-list: NEUR 415, ELEC 488, CMOR 415, NEUR 615, CMOR 615. Mutually Exclusive: Cannot register for ELEC 588 if student has credit for ELEC 488.