Course Catalog - 2022-2023



Department: Bioengineering
Grade Mode: Standard Letter
Language of Instruction: Taught in English
Course Type: Lecture
Credit Hours: 3
Must be enrolled in one of the following Level(s):
Description: Gene therapy suffered from major clinical setbacks in the late 1990’s, putting the entire field of genetic medicine at a standstill. However, through perseverance and strategic re-thinking of how viruses and cells could be used as therapeutics, the field is currently experiencing a biotechnological revolution. In December of 2017, a virus-based gene therapy drug was approved by the FDA, making it the first of its kind for the treatment of an inherited disease. This landmark achievement is just the beginning of a new era of human therapeutics. This class will discuss the gene therapy field – where it was and where it is now. Clinically important vectors currently under human testing, and opportunities for the next generation of improved gene delivery vectors will be presented. The biological and physiological barriers to efficient gene delivery will be investigated in order to spur new ideas for improving vector efficiency and specificity. Graduate/Undergraduate Equivalency: BIOE 422. Mutually Exclusive: Cannot register for BIOE 522 if student has credit for BIOE 422.