BIOS 481 - MOLECULAR BIOPHYSICS I
Long Title: MOLECULAR BIOPHYSICS I
Department: Biosciences
Grade Mode: Standard Letter
Language of Instruction: Taught in English
Course Type: Lecture
Credit Hours: 3
Restrictions: Must be enrolled in one of the following Level(s):
Undergraduate Professional
Visiting Undergraduate
Undergraduate
Prerequisite(s): BIOC 301 OR BIOS 301 OR BIOC 352 OR BIOS 352
Description: Focus on principles of common biophysical methods used for study of conformations and dynamics of biological macromolecules and assemblies. Topics cover spectroscopic methods (absorption, fluorescence, circular dichroism, epr, NMR), transport processes, sedimentation, calorimetry, mass spectrometry, crystallography, cryo-electron microscopy, atomic force microscopy, ligand-protein interactions, protein folding, single molecule detection, computer simulations, functional genomics and laboratory evolution. Biological examples will be used to demonstrate merits and complementarity in each of the biophysical methods. Graduate/Undergraduate Equivalency: BIOS 551.