Course Schedule and Catalog

Long Title: INTRO COMPUTATIONAL SYSTEMS BIOLOGY: MODELING & DESIGN PRINCIPLES OF BIOCHEM NETWORKS

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): (MATH 212 OR MATH 213) AND BIOS 314

Description: The course summarizes techniques for analysis and simulations of basic circuits in genetic regulation, signal transduction and metabolism and aims to formulate evolutionary design principles explaining organization of networks in terms of their physiological demands. Topics include end-product inhibition in biosynthesis, robustness of the signaling networks and kinetic proofreading. Students are expected to present several journal articles. Same as 490 but with project-report instead of final exam, individual rather than group presentation. Graduate/Undergraduate Equivalency: BIOE 490. Recommended Prerequisite(s): Basic knowledge of biochemistry, cell biology, linear algebra, and ordinary differential equations is expected. Mutually Exclusive: Cannot register for BIOE 552 if student has credit for BIOE 490.