Course Schedule and Catalog

Long Title: FUNDAMENTALS OF ELECTROPHYSIOLOGY

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: Introduction to cellular electrophysiology. Includes the development of whole-cell models for neurons and muscle (cardiac, skeletal and smooth muscle) cells, based on ion channel currents obtained from whole-cell voltage-clamp experiments. Ion balance equations are developed, as well as, those for chemical signaling agents such as "second messengers." The construction of small neuron circuits are discussed. Volume conductor boundary-value problems frequently encountered in electrophysiology are posed, and solutions obtained based on adequate descriptions of the bioelectric current source and the volume conductor (surrounding tissue) medium. This course provides a basis for the interpretation of macroscopic bioelectric signals such as the electrocardiogram (ECG), electromyogram (EMG) and electroencephalogram (EEG). Cross-list: ELEC 381.