Description: This course will address the biology, organization, mechanics, and turnover of extracellular matrix. There will be an emphasis on cells and cell-matrix interactions, matrix distribution within and design of connective tissues and organs techniques for quantitative analysis of matrix, techniques for measurement and modeling of connective tissue biomechanics, changes with growth and aging and tissue/matrix degradation. Additional projects will be required of graduate level students. Cross-list: BIOE 524, BIOE 464, BIOC 464. Recommended Prerequisite(s): BIOE 372, BIOC/BIOE 341. Mutually Exclusive: Cannot register for BIOC 523 if student has credit for BIOC 464.