Course Schedule and Catalog

Long Title: COMPUTATIONAL MOLECULAR BIOENGINEERING/BIOPHYSICS

Department: Bioengineering

Grade Mode: Standard Letter

Language of Instruction: Taught in English

Course Type: Lecture

Credit Hours: 3

Description: This is a course designed for students in computationally-oriented biomedical and bioengineering majors to introduce the principles and methods used for the simulations and modeling of macromolecules of biological interest. Protein conformation and dynamics are emphasized. Empirical energy function and molecular dynamics calculations are described. Specific biological problems are discussed to illustrate the methodology. Classic examples such as the cooperative mechanism of hemoglobin and more frontier topics such as the motional properties of molecular motors and ion channels as well as results derived from the current literature are covered. Cross-list: BIOC 589. Recommended Prerequisite(s): MATH 212, (BIOS 301 or BIOC 301), BIOE 332.