Course Schedule and Catalog

Long Title: SYSTEMS BIOLOGY OF BLOOD VESSELS

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOE 252

Description: How blood vessels respond to hypoxia is a process critical to the progression of many diseases and conditions including cardiovascular disease, cancer, cerebrovascular disease, diabetes, obesity and arthritis. Physiological processes such as exercise, aging, and wound healing also depend on hypoxia-induced microvessel changes. This course introduces engineering concepts of hypoxic response, angiogenesis, and capillary remodeling - from the effects at the intracellular level to the whole body. Topics covered include computational systems biology modeling of hypoxia and angiogenesis, the use of angiogenesis in tissue engineering and regenerative medicine, imaging of blood vessel dynamics, capillaries of the brain, and the design of new blood vessels. Graduate students will be required to complete a term research project and present a related short seminar. Graduate/Undergraduate Equivalency: BIOE 307. Mutually Exclusive: Cannot register for BIOE 507 if student has credit for BIOE 307.