BIOC 481 - MOLECULAR BIOPHYSICS I
Long Title: MOLECULAR BIOPHYSICS I
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
May not be enrolled in one of the following Level(s):
Prerequisite(s): BIOC 301 OR BIOC 352 or permission of instructor
Description: Focus on principles of common biophysical methods used for study of conformations and dynamics of biological macromolecules and assemblies. Topics cover spectroscopic methods (absorption, fluorescence, circular dichroism, epr, NMR), transport processes, sedimentation, calorimetry, mass spectrometry, crystallography, cryo-electron microscopy, atomic force microscopy, ligand-protein interactions, protein folding, single molecule detection, computer simulations, functional genomics and laboratory evolution. Biological examples will be used to demonstrate merits and complementarity in each of the biophysical methods. Graduate/Undergraduate Equivalency: BIOC 551.