Course Catalog - 2017-2018

     

BIOC 007 - VISITING RESEARCH

Long Title: VISITING RESEARCH
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Research
Credit Hours: 0
Description: Research conducted by visiting student scholars. Department Permission Required. Repeatable for Credit.
 

BIOC 111 - FUNDAMENTALS OF EXP BIOLOGY

Long Title: FUNDAMENTALS OF EXPERIMENTAL BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture/Laboratory
Credit Hours: 1
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: BIOC 111 introduces fundamental methods and standard practices in biosciences laboratories. In this goal-driven course, students work in teams to complete short investigative projects. Course is offered both halves of each semester. This course is recommended for students with very limited practical laboratory experience. Students wishing to take this course must have a pre-lab examination score on file with the Registrar; see the course URL for instructions. In the fall, BIOC 111 sections in the second half of the semester are restricted to new matrics only. Mutually Exclusive: Credit cannot be earned for BIOC 111 and BIOC 112.
Course URL: http://www.clear.rice.edu/bioc111/
 

BIOC 112 - INTRO BIOL RESEARCH CHALLENGES

Long Title: INTRODUCTORY BIOLOGICAL RESEARCH CHALLENGES
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Laboratory
Credit Hours: 1
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: Teams of students work on investigative, client-based projects with opportunities to design experiments, analyze data, and communicate their findings. This course is recommended for students interested in the Biochemistry and Cell Biology major who have very limited practical laboratory experience. Only first year students may enroll. Mutually Exclusive: Credit cannot be earned for BIOC 112 and BIOC 111.
 

BIOC 115 - FRESHMAN BIOLOGY SEMINAR (BCB)

Long Title: FRESHMAN SEMINAR IN LOCAL BIOLOGY RESEARCH (BCB)
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Seminar
Distribution Group: Distribution Group III
Credit Hours: 1
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: A 7-week seminar course to introduce freshmen prospective biologists to the excitement of research at Rice and the Medical Center and to provide context with which to think about facts presented in biosciences textbooks. Small groups will meet weekly with a graduate student or postdoctoral researcher to explore a published research article by a local lab, gaining background information about the subject and exposure to the research techniques. In the final session, the group will tour the lab that produced the featured article. Additional tours and activities TBA. All first-year non-transfer students are eligible to enroll in BIOC 115/FSEM 115 regardless of AP credit. This course meets in the second half of the semester and features research in the Program of Biochemistry and Cell Biology. Cross-list: FSEM 115.
Course URL: http://www.bioc.rice.edu/bioc115/
 

BIOC 122 - CURRENT TOPICS IN BIOLOGY

Long Title: CURRENT TOPICS IN BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Distribution Group: Distribution Group III
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: Students will learn methods of science and fundamental concepts related to biomolecules, cells, tissues, systems, evolution, development, and genetics through discussions of current and past biologically-related issues and controversies. Classroom attendance is required. Mutually Exclusive: Credit cannot be earned for BIOC 122 and BIOC 201.
Course URL: http://www.ruf.rice.edu/~bioslabs/bioc122/
 

BIOC 201 - INTRODUCTORY BIOLOGY

Long Title: INTRODUCTORY BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Distribution Group: Distribution Group III
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: Chemistry and energetics, cell physiology, cell biology, Mendelian genetics, molecular genetics, developmental biology, and plant physiology. Mutually Exclusive: Credit cannot be earned for BIOC 201 and BIOC 122/GLHT 122.
 

BIOC 205 - MICROBE HUNTERS REVISITED

Long Title: MICROBE HUNTERS REVISITED
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Seminar
Credit Hours: 2
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: This seminar will review important microbiologists and their discoveries of infectious agents. From Pasteur to Prusiner, we will review the infectious agents they described, as well as the methods used for their discovery. The classic text by Paul de Kruif entitled "Microbe Hunters" will be the basis for half of the course material.
 

BIOC 211 - EXPERIMENTAL BIOSCIENCES

Long Title: INTERMEDIATE EXPERIMENTAL BIOSCIENCES
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture/Laboratory
Credit Hours: 2
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 201 AND (BIOC 111 OR BIOC 112 OR NSCI 120)
Description: Introduction to scientific method, principles of experimental design, selected research strategies, record keeping, and technical communication as related to biological science. The prereq BIOC 201 may be taken concurrently with BIOC 211. Students matriculating fall 2009 or later who wish to take BIOC 211 must take BIOC 111 or test out of it. See the course URL for instructions.
Course URL: http://www.clear.rice.edu/bioc111/
 

BIOC 215 - BIOC LAB TEACHING

Long Title: BIOSCIENCES LAB TEACHING
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Laboratory
Credit Hours: 1 TO 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: Undergraduate teaching in a biosciences laboratory. Provide group and individual instruction and feedback to undergraduates during and outside of laboratory classes. Instructor Permission Required. Repeatable for Credit.
 

BIOC 216 - DISCUSSION SECTION TEACHING

Long Title: DISCUSSION SECTION TEACHING
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Independent Study
Credit Hours: 1
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: In this course, undergraduates who have previously excelled in a BIOC course, as approved by the Department Chair for this activity, will develop teaching skills by leading discussion sections or serving as writing mentors. These activities are designed to benefit students presently taking the relevant BIOC course and will be performed under the guidance of the professor teaching the course. Instructor Permission Required. Repeatable for Credit.
 

BIOC 220 - FORENSIC BIOL & CRIMINALISTICS

Long Title: FORENSIC BIOLOGY AND CRIMINALISTICS
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 201 or permission of instructor
Description: This course will introduce students to certain areas of forensic science including - crime scene analysis, forensic serology, molecular genetics (DNA), forensic toxicology; drugs, and the identification of biological fluids such as blood, saliva, and semen, with case studies and a potential field trip. The course is designed for biology and chemistry students, for students interested in the application of biosciences in DNA and crime scene analysis.
 

BIOC 300 - PARADIGMS IN BIOCHM & CELL BIO

Long Title: PARADIGMS IN BIOCHEMISTRY AND CELL BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: Examination of paradigms in Biochemistry and Cell Biology with a focus on the "central dogma" of molecular biology. Recommended strongly for students with Advanced Placement in Biology and designed for prospective BIOC majors. This course is strongly recommended as preparation for BIOC 341 (Cell Biology). RESTRICTIONS: If taken one semester before taking any other 300-level BIOC course, this course can count as a 300-level Natural Science/Engineering Elective (for those majoring in Biochemistry and Cell Biology), or as an elective 300 level BIOC lecture course (for those majoring in Biological Sciences). Recommended strongly for students with Advanced Placement in Biology and designed for prospective BIOC majors. For students with AP credit for BIOS/BIOC 201, this course is strongly recommended as preparation for BIOC 341 (Cell Biology).
 

BIOC 301 - BIOCHEMISTRY I

Long Title: BIOCHEMISTRY I
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): CHEM 211 AND BIOC 201
Description: The second in an integrated sequence of three courses (BIOC 201, 301, 302). Structure and function of proteins, enzymes, and nucleic acids; enzyme kinetics; glycolysis, aerobic metabolism, and energy coupling. Recommended Prerequisite(s): CHEM 212.
 

BIOC 302 - BIOCHEMISTRY II

Long Title: BIOCHEMISTRY II
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 301
Description: The final in an integrated sequence of three courses (BIOC 201, 301, 302). In depth study of carbohydrate, amino acid, and lipid metabolic pathways, hormone regulation of metabolic path ways, key cell signaling mechanisms, and the structural biology of DNA replication, transcription, and translation into proteins. Course also involves analysis of primary scientific literature. Recommended Prerequisite(s): CHEM 212 or CHEM 320.
 

BIOC 305 - INVESTIGATIVE BIOCHEMISTRY

Long Title: INVESTIGATIVE BIOCHEMISTRY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture/Laboratory
Credit Hours: 2
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
May not be enrolled in one of the following Major(s):
Biological Sciences
Biochemistry and Cell Biology
Must be enrolled in one of the following Class(es):
Senior
Junior
Prerequisite(s): BIOC 301 AND (BIOC 111 OR BIOC 112 OR NSCI 120)
Description: In this course designed for premedical students not majoring in the Biosciences, students work in teams to complete part of a research project. In addition to gaining practical laboratory experience in biochemistry, students maintain a laboratory notebook, generate and analyze data, and write a research paper. The prerequisite BIOC 301 may be taken concurrently with BIOC 305.
 

BIOC 310 - IND RES FOR BIOC UNDERGRADS

Long Title: INDEPENDENT RESEARCH FOR BIOCHEMISTRY AND CELL BIOLOGY UNDERGRADUATES
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Research
Credit Hours: 1 TO 4
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 111 OR BIOC 211
Description: Independent research in Rice BCB faculty laboratories (sections 3 and above) or other Texas Medical Center laboratories (sections 1 & 2). Students spend at least 3 hours per week in the laboratory for each semester hour of credit. If taken for 3 or more hours, counts as one required 300+ level lab course (not BIOC 311). Requires a proposal abstract, weekly reports, and a research paper (fall semester) or a proposal abstract, weekly reports, and a poster presentation (spring semester). Students wishing to perform their research in an off-campus lab must submit a completed application to the BIOC 310 instructor at least 2 weeks prior to the start of classes and may not register for fewer than 3 credit hours. Instructor Permission Required. Recommended: Instructor permission. Students are strongly advised to secure research advisors and register for the class well in advance of the start of classes. Repeatable for Credit.
Course URL: http://www.bioc.rice.edu/bioc310
 

BIOC 311 - ADV EXPERIMENTAL BIOSCIENCES

Long Title: ADVANCED EXPERIMENTAL BIOSCIENCES
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture/Laboratory
Credit Hours: 2
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
May not be enrolled in one of the following Class(es):
Freshman
Prerequisite(s): BIOC 211 AND BIOC 301
Description: Advancement of biochemical laboratory methods, record keeping, technical communication skills, and research strategies. Students will maintain a research quality laboratory notebook and will submit a paper in the style of a journal article. Offered first half of each semester and in Summer Session I. Pre-req BIOC 301 may be taken concurrently with BIOC 311. BIOC 301 (formerly BIOS 301) is required but it can be taken during the same semester as BIOC 311.
Course URL: http://www.owlnet.rice.edu/~bios311/bios311/311homepage.html
 

BIOC 313 - INTRODUCTORY SYNTHETIC BIO

Long Title: INTRODUCTORY SYNTHETIC BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture/Laboratory
Credit Hours: 2
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOS 211 OR BIOC 211 or permission of instructor
Description: Students learn molecular biological procedures commonly used to build and characterize synthetic genetic circuits. Teams of students work on a research project in the interdisciplinary field of synthetic biology. Students continue to develop technical communication skills.
Course URL: http://www.owlnet.rice.edu/~bios311/bios311/bios313/bios313.html
 

BIOC 318 - LAB MODULE IN MICROBIOLOGY

Long Title: LABORATORY STUDIES IN APPLIED MICROBIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture/Laboratory
Credit Hours: 1
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 211
Description: Team projects focusing on water analysis and isolation, culture, observation, assay, and identification of bacteria. Offered in the second half of each semester, self-scheduled after the first formal meetings.
Course URL: http://www.ruf.rice.edu/~bioslabs/bios318/
 

BIOC 320 - LABORATORY IN TISSUE CULTURE

Long Title: LABORATORY IN TISSUE CULTURE
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Laboratory
Credit Hours: 1
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOE 440 OR STAT 440 OR BIOC 311
Description: Introduction to tissue culture techniques, including cell passage, cell viability, and cell attachment and proliferation assays. Students complete quantitative analysis of their data. Engineering design and applications are featured in graded work. Sections 1 and 2 are taught during the first half of the semester. Sections 3 and 4 are taught during the second half of the semester. Students may be required to attend lab on a university holiday. Instructor Permission Required.Cross-list: BIOE 342.
 

BIOC 329 - ANIMAL BIOLOGY AND PHYSIOLOGY

Long Title: ANIMAL BIOLOGY AND PHYSIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Distribution Group: Distribution Group III
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 201 OR EBIO 202
Description: The evolution and systematics of the animal kingdom with consideration of functional anatomy, comparative physiology, behavior, medical implications and resource management. Cross-list: EBIO 329. Mutually Exclusive: Credit cannot be earned for BIOC 329 and EBIO 529.
 

BIOC 331 - BIOLOGY OF INFECTIOUS DISEASES

Long Title: BIOLOGY OF INFECTIOUS DISEASES
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Distribution Group: Distribution Group III
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): EBIO 213
Description: This course gives a broad overview of the biology of infectious diseases using examples from humans, plants, and animals. Topics include diversity of diseases, mechanisms of disease transmission, epidemiology, population regulation, evolution of virulence, disease dynamics in natural communities and disease invasion and conservation biology. Cross-list: EBIO 331.
 

BIOC 332 - SYSTEMS PHYSIOLOGY

Long Title: SYSTEMS PHYSIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 201 AND (PHYS 101 AND PHYS 102) OR (PHYS 125 AND PHYS 126)
Description: This course will teach the fundamentals of human physiology with a specific focus on the nervous, cardiovascular, respiratory, and urinary systems. Basic introductory engineering principles will be applied to the study of physiological systems. The course is aimed to be accessible to students with non-engineering backgrounds. Students may receive credit for only one of BIOE 302, BIOE 322, and BIOC 332. Cross-list: BIOE 302. Mutually Exclusive: Credit cannot be earned for BIOC 332 and BIOE 322.
 

BIOC 334 - EVOLUTION

Long Title: EVOLUTION
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Distribution Group: Distribution Group III
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): EBIO 202 or permission of instructor
Description: Principles of biological evolution. Topics include natural selection, adaptation, molecular evolution, formation of new species, the fossil record, biogeography, and principles of classification. Cross-list: EBIO 334.
Course URL: http://www.ruf.rice.edu/~queller/Bios334/
 

BIOC 335 - CELL & MOL ANIMAL PHYSIOLOGY

Long Title: CELLULAR AND MOLECULAR ANIMAL PHYSIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 201
Description: This course takes a functional approach to investigate animal physiology from a cellular and molecular perspective. Using an integrated and comparative approach, students learn how animals maintain homeostasis, including how they meet their energy needs, take up and transport oxygen, and maintain hydration and salt balance. Students will read primary literature to explore physiological adaptations for survival in extreme environments. Graduate/Undergraduate Equivalency: BIOC 536. Mutually Exclusive: Credit cannot be earned for BIOC 335 and BIOC 536.
 

BIOC 341 - CELL BIOLOGY

Long Title: CELL BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Distribution Group: Distribution Group III
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 201
Description: Molecular mechanisms of eukaryotic cell function. Structure, function, and biogenesis of all subcellular organelles. Cell-cell communication, cytoskeleton assembly and function, cell cycle control, and cell-cell adhesions. Emphasis will be on cytoplasmic events; molecular studies of transcription are taught in BIOC 302 and BIOC 344. RECOMMENDATION: BIOC 300 is recommended for students using advanced placement credit for BIOC 201 and students preferring additional foundational background prior to enrollment in BIOC 341.
 

BIOC 344 - MOLECULAR BIOLOGY & GENETICS

Long Title: MOLECULAR BIOLOGY AND GENETICS
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Distribution Group: Distribution Group III
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: Mendelian genetics, population genetics, mapping, gene expression and regulation, genetic engineering, DNA replication and recombination, human genetics, genetic disease and gene therapy. Recommended Prerequisite(s): BIOC 201.
 

BIOC 352 - PHYS CHEM FOR BIOSCIENCES

Long Title: PHYSICAL CHEMISTRY FOR THE BIOSCIENCES
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): (PHYS 126 OR PHYS 102 OR PHYS 112 OR PHYS 142) AND BIOC 301
Description: Study of selected aspects of physical chemistry as it relates to the biosciences. Includes thermodynamics, reaction rate theory, quantum mechanics, and atomic and molecular structure.
 

BIOC 361 - METAB ENG GLOBAL HEALTH ENVMNT

Long Title: METABOLIC ENGINEERING FOR GLOBAL HEALTH ENVIRONMENTS
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): (BIOE 362 OR GLHT 362) AND (PHYS 126 OR PHYS 102 OR PHYS 112 OR PHYS 142) AND MATH 102
Description: Importance of nutritional and pharmaceutical compounds, impact of cost of compounds on global health; Overview of biochemical pathways; metabolite analysis; Genetic engineering and molecular biology tools for ME; Pharmaceuticals and drug discovery approaches (antibiotics, antivirals; anti-parasite compounds); anti-diarrhea treatments; vaccines. Cross-list: BIOE 361, GLHT 361.
Course URL: http://www.btb.rice.edu
 

BIOC 368 - MONSTER

Long Title: CONCEIVING AND MISCONCEIVING THE MONSTROUS IN FICTION AND IN ART, IN MEDICINE AND IN BIOSCIENCE
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Seminar
Distribution Group: Distribution Group III
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: However various the forms of life, we draw boundaries between the "normal," the "not normal," and the "monstrous." From the Biosciences to the Arts - from the cyclopean eye to Frankenstein - monsters illuminate (whether in fact or in fiction) who we are, how we perceive, and what we fear. Cross-list: HUMA 368.
 

BIOC 371 - BIOMEDICAL RESEARCH SEMINAR

Long Title: SEMINAR IN CONTEMPORARY BIOLOGICAL AND BIOMEDICAL RESEARCH
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Seminar
Credit Hours: 1
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 341 OR BIOC 301
Description: This course will offer students a close-up look at an area of contemporary biological and biomedical research in a small-group seminar setting. Each seminar will focus on a different area of research through reading and discussion of recent research articles in that focus area. The faculty discussion leader for each seminar will be drawn from Baylor College of Medicine, UT Health Science Center, MD Anderson Cancer Center, Rice and others. Please consult the course website for a complete listing of seminars offered each semester. Please refer to the following link for additional information: http://www.bioc.rice.edu/bioc371. Instructor Permission Required. Students should check the courses website for additional prerequisites, notes from the instructor, and other information specific to each section. Repeatable for Credit.
Course URL: http://www.bioc.rice.edu/bioc371
 

BIOC 372 - IMMUNOLOGY

Long Title: IMMUNOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Distribution Group: Distribution Group III
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 201
Description: Cellular and molecular basis of innate and adaptive immune function in mammals. Graduate/Undergraduate Equivalency: BIOC 573. Recommended Prerequisite(s): BIOC 301 and BIOC 341. Mutually Exclusive: Credit cannot be earned for BIOC 372 and BIOC 573/BIOS 372.
 

BIOC 380 - NEUROSYSTEMS

Long Title: FUNDAMENTAL NEUROSCIENCE SYSTEMS
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: This course will provide a broad overview of the brain's neural systems that subserve perception, learning, and behavior. The course will be highly integrative with thematic content including functional organization of the nervous system, neural encoding and decoding, sensory systems, motor systems, and high-level concept processing. Cross-list: NEUR 380, PSYC 380. Recommended Prerequisite(s): PSYC 101.
 

BIOC 385 - FUNDAMENTALS OF NEUROSCIENCE

Long Title: FUNDAMENTALS OF CELLULAR AND MOLECULAR NEUROSCIENCE
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Distribution Group: Distribution Group III
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: Cellular, molecular, and integrative mechanisms of neural function, including membrane and axon physiology, synaptic transmission and plasticity, sensory transduction and processing. Cross-list: NEUR 385, Graduate/Undergraduate Equivalency: BIOC 585. Recommended Prerequisite(s): BIOC 201. Mutually Exclusive: Credit cannot be earned for BIOC 385 and BIOC 585.
 

BIOC 390 - TRAN CREDIT BIOCHEM&CELL BIO

Long Title: TRANSFER CREDIT IN BIOCHEMISTRY AND CELL BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Transfer
Credit Hours: 3
Description: For transfer of courses which have no current equivalent in the Rice curriculum, but which can be counted as 300 level BIOC lecture courses, in satisfying requirements for majors in Biosciences. Repeatable for Credit.
 

BIOC 393 - LAB TRANSFER CREDIT

Long Title: LABORATORY TRANSFER CREDIT IN BIOCHEMISTRY AND CELL BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Transfer
Credit Hours: 1
Description: For transfer of an advanced laboratory course in the Biochemistry and Cell Biology that has no current equivalent in the Rice curriculum. Any student may receive a maximum of one credit of BIOC 393.
 

BIOC 401 - UNDERGRADUATE HONORS RESEARCH

Long Title: UNDERGRADUATE HONORS RESEARCH
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Research
Credit Hours: 5
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Description: The Biochemistry and Cell Biology Honors Research Program is a suite of courses offering our seniors and advanced juniors the opportunity to perform a two-semester, individual research project in a research laboratory in Biochemistry & Cell Biology. Students having performed BIOS/BIOC 310 research in an off-campus laboratory in the Texas Medical Center will also be eligible to apply to perform honors research in that laboratory. The Honors Research Program courses function as a set and must all be taken in the same academic year. Registration for any of the courses requires a commitment to register for all three. Requires at least 15 hours of laboratory research per week, a proposal (revised from application), monthly reports, and a formal progress report (abstract, aims, progress toward aims, discussion of results, plans for the spring semester). Prerequisites: strong performance in (BIOC 310, or HONS 470/471) and BIOC 211 and either BIOC 301 or BIOC 341. Research professor recommendation required. Application for admission required (BCB Honors Program OwlSpace Resources). Department Permission Required. Repeatable for Credit.
 

BIOC 402 - UNDERGRADUATE HONORS RESEARCH

Long Title: UNDERGRADUATE HONORS RESEARCH
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Research
Credit Hours: 5
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 401
Corequisite: BIOC 412
Description: The Biochemistry and Cell Biology Honors Research Program is a suite of courses offering our seniors and advanced juniors the opportunity to perform a two-semester, individual research project in a research laboratory in Biochemistry & Cell Biology. Students having performed BIOS/BIOC 310 research in an off-campus laboratory in the Texas Medical Center will also be eligible to apply to perform honors research in that laboratory. Registration for any of the courses requires a commitment to register for all three. Requires at least 15 hours of laboratory research per week, monthly reports, a thesis (substantial research paper) and a poster presentation at the Rice Undergraduate Research Symposium. Repeatable for Credit.
 

BIOC 412 - UNDERGRADUATE RESEARCH SEMINAR

Long Title: UNDERGRADUATE RESEARCH SEMINAR
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Seminar
Credit Hours: 1
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 401
Corequisite: BIOC 402
Description: This companion seminar requires attendance at course meetings and a formal scientific presentation of research performed while enrolled in the Honors Research Program. Repeatable for Credit.
 

BIOC 413 - EXPERIMENTAL MOLECULAR BIO

Long Title: EXPERIMENTAL MOLECULAR BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Laboratory
Credit Hours: 1
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 311 or permission of instructor
Description: Application of strategies in molecular biology to investigate gene expression and function with an emphasis on experimental design, data analysis, and data interpretation. Students will prepare a scientific poster. Offered second half of spring semester.
Course URL: http://www.owlnet.rice.edu/~bios311/bios311/bios413/bios413.html
 

BIOC 415 - EXPERIMENTAL PHYSIOLOGY

Long Title: EXPERIMENTAL PHYSIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture/Laboratory
Credit Hours: 1
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 311
Description: Laboratory studies in membrane, nerve, and muscle physiology, with emphasis on experimental design, data analysis, and data interpretation.
Course URL: http://www.ruf.rice.edu/~bioslabs/bios415
 

BIOC 424 - MICROBIOLOGY & BIOTECHNOLOGY

Long Title: MICROBIOLOGY AND BIOTECHNOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 201 or permission of instructor
Description: Structure and functions of microorganisms with emphasis on their environmental, industrial and medical importance. Graduate/Undergraduate Equivalency: BIOC 524. Recommended Prerequisite(s): BIOC 301 or Instructor Permission. Mutually Exclusive: Credit cannot be earned for BIOC 424 and BIOC 524.
 

BIOC 425 - PLANT MOLECULAR GENETICS

Long Title: PLANT MOLECULAR GENETICS AND DEVELOPMENT
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 301 OR BIOC 341 or permission of instructor
Description: Novel aspects of plant biology and development with emphasis on molecular and genetic mechanisms. Plant responses to the environment and the use of bioengineering and other means to develop new plant products will also be covered. Graduate/Undergraduate Equivalency: BIOC 525. Mutually Exclusive: Credit cannot be earned for BIOC 425 and BIOC 525.
 

BIOC 443 - DEVELOPMENT

Long Title: ADVANCED CONCEPTS AND CRITICAL ANALYSIS IN MODERN DEVELOPMENTAL BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 341 OR BIOC 301 OR BIOC 344 or permission of instructor
Description: An advanced undergraduate and graduate level course, dedicated to analysis and evaluation of scientific inquiry into animal development. Textbook based lectures and discussions based on primary scientific literature are used to exemplify and evaluate concepts and methodology. Writing assignments, quizzes, midterm and final exam will be used to evaluate performance. Graduate/Undergraduate Equivalency: BIOC 544. Mutually Exclusive: Credit cannot be earned for BIOC 443 and BIOC 544.
 

BIOC 445 - ADV MOLECULAR BIOL & GENETICS

Long Title: ADVANCED MOLECULAR BIOLOGY AND GENETICS
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 301 OR BIOC 344
Description: Molecular and genetic aspects of the regulation of gene expression as seen in simple prokaryotic systems and the model eukaryotic systems used for studies of development. Graduate/Undergraduate Equivalency: BIOC 545. Mutually Exclusive: Credit cannot be earned for BIOC 445 and BIOC 545.
 

BIOC 447 - BIOLOGY AND MEDICINE

Long Title: EXPERIMENTAL BIOLOGY AND THE FUTURE OF MEDICINE
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 301 OR BIOC 341 OR BIOC 344
Description: Current biological methods offer the potential to transform health care. We will examine the biology and methodology of emergent health care technologies such as stem cell therapy and personal genome sequencing to understand their potential to impact human health. Graduate/Undergraduate Equivalency: BIOC 547.
 

BIOC 450 - VIRUSES & INFECTIOUS DISEASES

Long Title: VIRUSES AND INFECTIOUS DISEASES
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 201 AND BIOC 301 AND BIOC 341 or permission of instructor
Description: Animal viruses, especially those relevant to human health, will be discussed. Topics primarily focus on virus structure and the molecular biology of the virus life cycle. Practical issues such as the history of viral diseases, clinical manifestations, laboratory diagnosis, management and prevention will also be discussed. Graduate/Undergraduate Equivalency: BIOC 550. Mutually Exclusive: Credit cannot be earned for BIOC 450 and BIOC 550.
 

BIOC 455 - COMP SYNTHETIC BIOLOGY

Long Title: COMPUTATIONAL SYNTHETIC BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): MATH 211
Description: Mathematical and computational techniques of cell biology and synthetic biology. Topics include deriving and implementing mathematical and computational models of cellular growth and division, evolution, gene regulation, synthetic gene circuits, enzymatic processing, and stochastic processes in biology. Graduate/Undergraduate Equivalency: BIOC 555. Recommended Prerequisite(s): CAAM 210
 

BIOC 460 - CANCER BIOLOGY

Long Title: CANCER BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 301 AND BIOC 341
Description: Provides an integrated lecture series summarizing current knowledge in cancer biology and integrating current literature with basic concepts. Topics include: statistics of incidence/survival, types of cancer, pathology, the process of carcinogenesis and sources of carcinogens, genetic and epigenetic mechanisms and consequences, cancer progression, metastasis and current treatment options. Students will learn to use online databases to develop independent strategies for analyzing datasets. There will be several writing assignments and in class oral presentations of research articles. This course requires instructor permission to enroll. Please fill out the special registration form from https://registrar.rice.edu/student/special_registration. All requests will be reviewed and you will be notified of an enrollment decision. Graduate/Undergraduate Equivalency: BIOC 560. Mutually Exclusive: Credit cannot be earned for BIOC 460 and BIOC 560.
 

BIOC 463 - ENDOCRINOLOGY

Long Title: ENDOCRINOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 201 AND BIOC 301 AND BIOC 341
Description: Study of the action of mammalian hormones in terms of whole organismal physiological responses and intracellular molecular signaling pathways. Graduate/Undergraduate Equivalency: BIOC 563. Mutually Exclusive: Credit cannot be earned for BIOC 463 and BIOC 363/BIOC 563.
 

BIOC 464 - EXTRACELLULAR MATRIX

Long Title: EXTRACELLULAR MATRIX
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 341
Description: This course will address the biology, organization, mechanics, and turnover of extracellular matrix. There will be an emphasis on cells and cell-matrix interactions, matrix distribution within and design of connective tissues and organs techniques for quantitative analysis of matrix, techniques for measurement and modeling of connective tissue biomechanics, changes with growth and aging and tissue/matrix degradation. Cross-list: BIOE 464, Graduate/Undergraduate Equivalency: BIOC 523. Recommended Prerequisite and Corequisite: BIOE 372, BIOC 341. Mutually Exclusive: Credit cannot be earned for BIOC 464 and BIOC 523.
 

BIOC 470 - COMPUTATION WITH BIOL DATA

Long Title: COMPUTATION WITH BIOLOGICAL DATA
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): (BIOC 301 OR BIOC 341 OR BIOC 344) AND MATH 102
Description: This course will teach programming and analysis techniques essential for modern research in the biological sciences. Students will learn the basics of programming in the MATLAB or Python scripting languages and applications to analyzing biological data. There will be a particular focus on quantitative image and sequence analysis. Graduate/Undergraduate Equivalency: BIOC 570. Mutually Exclusive: Credit cannot be earned for BIOC 470 and BIOC 570.
 

BIOC 481 - MOLECULAR BIOPHYSICS I

Long Title: MOLECULAR BIOPHYSICS I
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 301 OR BIOC 352 or permission of instructor
Description: Focus on principles of common biophysical methods used for study of conformations and dynamics of biological macromolecules and assemblies. Topics cover spectroscopic methods (absorption, fluorescence, circular dichroism, epr, NMR), transport processes, sedimentation, calorimetry, mass spectrometry, crystallography, cryo-electron microscopy, atomic force microscopy, ligand-protein interactions, protein folding, single molecule detection, computer simulations, functional genomics and laboratory evolution. Biological examples will be used to demonstrate merits and complementarity in each of the biophysical methods. Graduate/Undergraduate Equivalency: BIOC 551.
 

BIOC 482 - STRUCTURAL BIOLOGY

Long Title: STRUCTURAL BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
May not be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 301 AND (PHYS 101 OR PHYS 125) AND (PHYS 102 OR PHYS 126) or permission of instructor
Description: Structural biology plays an important role in defining atomic structures of biomolecules and understanding relationships between structure, dynamics and function in living systems. This course will give an introduction to techniques of determining biomolecular structures, X-ray crystallography, NMR, and cryoelectron microscopy and discuss striking examples of the power of structural biology. Graduate/Undergraduate Equivalency: BIOC 552. Mutually Exclusive: Credit cannot be earned for BIOC 482 and BIOC 552.
 

BIOC 520 - TEACHING BIOLOGY ACTIVELY I

Long Title: TEACHING BIOLOGY VIA ACTIVE LEARNING I
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Seminar
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: First semester of a one-year sequence. Using the Scientific Teaching Approach, this course will teach teachers how to use active learning to engage students and provide teachers with in depth conceptual knowledge about biological fundamentals. This course will include hands-on-activities and discussions about biological concepts that include enzymes, mitosis and meiosis, genetics, biotechnology, natural selection and evolution. Connection themes in biology will be highlighted throughout the course. Instructor permission required. Instructor Permission Required.
 

BIOC 521 - TEACHING BIOLOGY ACTIVELY II

Long Title: TEACHING BIOLOGY VIA ACTIVE LEARNING II
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Seminar
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Second semester of a one year sequence. Using the Scientific Teaching Approach, this course will teach teachers how to use active learning to engage students and provide teachers with in depth conceptual knowledge about biological fundamentals. This course will include hands-on-activities and discussions about biological concepts that include enzymes, mitosis and meiosis, genetics, biotechnology, natural selection and evolution. Connection themes in biology will be highlighted throughout the course. Recommended Prerequisite: BIOC 520. Instructor permission required. Instructor Permission Required.
 

BIOC 523 - EXTRACELLULAR MATRIC

Long Title: EXTRACELLULAR MATRIX
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: This course will address the biology, organization, mechanics, and turnover of extracellular matrix. There will be an emphasis on cells and cell-matrix interactions, matrix distribution within and design of connective tissues and organs techniques for quantitative analysis of matrix, techniques for measurement and modeling of connective tissue biomechanics, changes with growth and aging and tissue/matrix degradation. Additional projects will be required of graduate level students. Cross-list: BIOE 524, Graduate/Undergraduate Equivalency: BIOC 464. Recommended Prerequisite and Corequisite: BIOE 372, BIOC/BIOE 341. Mutually Exclusive: Credit cannot be earned for BIOC 523 and BIOC 464.
 

BIOC 524 - MICROBIOLOGY & BIOTECHNOLOGY

Long Title: MICROBIOLOGY & BIOTECHNOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Structure and functions of microorganisms with emphasis on their environmental, industrial and medical importance. Graduate/Undergraduate Equivalency: BIOC 424. Mutually Exclusive: Credit cannot be earned for BIOC 524 and BIOC 424.
 

BIOC 525 - PLANT MOLECULAR GENETICS

Long Title: PLANT MOLECULAR GENETICS AND DEVELOPMENT
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Novel aspects of plant biology and development with emphasis on molecular and genetic mechanisms. Plant responses to the environment and the use of bioengineering and other means to develop new plant products will also be covered Graduate/Undergraduate Equivalency: BIOC 425. Mutually Exclusive: Credit cannot be earned for BIOC 525 and BIOC 425.
 

BIOC 530 - LAB MOD NMR SPECTROSCOPY&MOLEC

Long Title: LAB MODULE IN NMR SPECTROSCOPY AND MOLECULAR MODELING
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Laboratory
Credit Hours: 1
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 481 OR BIOC 482 OR BIOC 552 OR BIOC 551 or permission of instructor
Description: The students will learn to set up, acquire, and process one-dimensional and basic two-dimensional NMR experiments. Spectral interpretation (3D molecular modeling of proteins and nucleic acids) for nucleic acids and proteins using homonuclear and heteronuclear data. Enrollment limited to 12, with priority to graduate students. Offered first half of the semester. BIOC 482/552 may be taken concurrently with BIOC 530.
 

BIOC 532 - LAB MOD OPTICAL SPECTROSCOPY

Long Title: LABORATORY MODULE IN OPTICAL SPECTROSCOPY AND KINETICS
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Laboratory
Credit Hours: 2
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Students learn the principles behind fluorescence, circular dichroism, analytical ultracentrifugation, spectroscopy and rapid kinetics by carrying out experiments with genetically engineered proteins and state-of-the-art equipment. Data will be interpreted and manipulated using curve-fitting and graphics software. Offered second half of the semester. Recommended Prerequisite(s): BIOC 352 or equivalent. Concurrent or previous enrollment in BIOC 481 or BIOC 551.
 

BIOC 533 - BIOINFORMATICS

Long Title: BIOINFORMATICS & COMPUTATIONAL BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 2
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: An introduction to the emerging field of bioinformatics. A series of lectures, combined with hands-on exercises. The topics to be discussed include sequence comparison, structure analysis, phylogenetics, database searching, microarrays and proteomics. Recommended prerequisite(s): BIOC 301 or permission of instructor.
 

BIOC 535 - PRACT X-RAY CRYSTALLOGRAPHY

Long Title: PRACTICAL X-RAY CRYSTALLOGRAPHY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture/Laboratory
Credit Hours: 2
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 552 OR BIOC 482
Description: This is an introduction to macromolecular crystallography with emphasis on crystallization methods, data acquisition, processing and molecular model-building. Approaches to solving structures will be discussed, as well as refinement of molecular models. Offered second half of the semester. Prerequisities are concurrent and may be taken the same semester.
 

BIOC 536 - CELL & MOL ANIMAL PHYSIOLOGY

Long Title: CELLULAR AND MOLECULAR ANIMAL PHYSIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: This course investigates animal physiology from a cellular and molecular perspective. Using an integrated and comparative approach, students learn how animals maintain homeostasis. Students will read primary literature to explore physiological adaptations for survival in extreme conditions. Graduate/Undergraduate Equivalency: BIOC 335. Mutually Exclusive: Credit cannot be earned for BIOC 536 and BIOC 335.
 

BIOC 537 - ADV CRYSTALLOGRAPHY SEMINAR

Long Title: ADVANCED CRYSTALLOGRAPHY SEMINAR
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Seminar
Credit Hours: 1
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 482 AND BIOC 535
Description: One hour seminar course in theoretical and practical aspects of crystallography, primarily as it applies to macromolecular crystallography. Presentations will be given by instructors and students on advanced topics based on published works or original research. Repeatable for Credit.
 

BIOC 540 - METABOLIC ENGINEERING

Long Title: METABOLIC ENGINEERING
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Principles of metabolic engineering: overview of biochemical pathways; kinetics and thermodynamics of metabolic networks; genetic engineering and molecular biology tools; metabolic flux analysis using stoichiometric and labeling techniques; metabolic control analysis. Metabolic engineering in the postgenomic era; functional genomics and systems biology. Emerging applications: chemicals from biorenewables; food ingredients; health and disease. Cross-list: CHBE 640.
 

BIOC 543 - SECONDARY METABOLISM

Long Title: SECONDARY METABOLISM
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): CHEM 212 OR CHEM 320
Description: A survey of the biosynthetic pathways leading to the major classes of natural products. Topics covered include the use of radioactive and stable isotopes, the synthesis of labeled organic compounds, mechanistic investigations of secondary metabolic enzymes, and the cloning and characterization of secondary metabolic genes.
 

BIOC 544 - DEVELOPMENT

Long Title: ADVANCED CONCEPTS AND CRITICAL ANALYSIS IN MODERN DEVELOPMENTAL BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 341 OR BIOC 301 OR BIOC 344 or permission of instructor
Description: An advanced undergraduate and graduate level course, dedicated to analysis and evaluation of scientific inquiry into animal development. Textbook based lectures and discussions based on primary scientific literature are used to exemplify and evaluate concepts and methodology. Writing assignments, quizzes, midterm and final exam will be used to evaluate performance. Graduate/Undergraduate Equivalency: BIOC 443. Mutually Exclusive: Credit cannot be earned for BIOC 544 and BIOC 443.
 

BIOC 545 - ADV MOLECULAR BIOL & GENETICS

Long Title: ADVANCED MOLECULAR BIOLOGY AND GENETICS
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Molecular and genetic aspects of the regulation of gene expression as seen in simple prokaryotic systems and the model eukaryotic systems used for studies of development. Graduate/Undergraduate Equivalency: BIOC 445. Mutually Exclusive: Credit cannot be earned for BIOC 545 and BIOC 445.
 

BIOC 547 - BIOLOGY AND MEDICINE

Long Title: EXPERIMENTAL BIOLOGY AND THE FUTURE OF MEDICINE
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Current biological methods offer the potential to transform health care. We will examine the biology and methodology of emergent health care technologies such as stem cell therapy and personal genome sequencing to understand their potential to impact human health. Graduate/Undergraduate Equivalency: BIOC 447. Recommended Prerequisite(s): BIOC 301 or BIOC 341 or BIOC 344.
 

BIOC 550 - VIRUSES & INFECTIOUS DISEASES

Long Title: VIRUSES AND INFECTIOUS DISEASES
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 201 AND BIOC 301 AND BIOC 341 or permission of instructor
Description: Animal viruses, especially those relevant to human health, will be discussed. Topics primarily focus on virus structure and the molecular biology of the virus life cycle. Practical issues such as the history of viral diseases, clinical manifestations, laboratory diagnosis, management and prevention will also be discussed. Graduate/Undergraduate Equivalency: BIOC 450. Mutually Exclusive: Credit cannot be earned for BIOC 550 and BIOC 450.
 

BIOC 551 - MOLECULAR BIOPHYSICS I

Long Title: MOLECULAR BIOPHYSICS
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 301 OR BIOC 352
Description: Focus on principles of common biophysical methods used for study of conformations and dynamics of biological macromolecules and assemblies. Topics cover spectroscopic methods (absorption, fluorescence, circular dichroism, epr, NMR), transport processes, sedimentation, calorimetry, mass spectrometry, crystallography, cryo-electron microscopy, atomic force microscopy, ligand-protein interactions, protein folding, single molecule detection, computer simulations, functional genomics and laboratory evolution. Biological examples will be used to demonstrate merits and complementarity in each of the biophysical methods. Graduate/Undergraduate Equivalency: BIOC 481.
 

BIOC 552 - STRUCTURAL BIOLOGY

Long Title: STRUCTURAL BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): (PHYS 101 OR PHYS 125) AND (PHYS 102 OR PHYS 126)
Description: Structural biology plays an important role in defining atomic structures of biomolecules and understanding relationships between structure, dynamics and function in living systems. This course will give an introduction to techniques of determining biomolecular structures, X-ray crystallography, NMR, and cryoelectron microscopy and discuss striking examples of the power of structural biology. Graduate/Undergraduate Equivalency: BIOC 482. Recommended prerequisite(s): BIOC 301. Mutually Exclusive: Credit cannot be earned for BIOC 552 and BIOC 482.
 

BIOC 555 - COMP SYNTH BIOLOGY

Long Title: COMPUTATIONAL SYNTHETIC BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Mathematical and computational techniques of cell biology and synthetic biology. Topics include deriving and implementing mathematical and computational models of cellular growth and division, evolution, gene regulation, synthetic gene circuits, enzymatic processing, and stochastic processes in biology. Graduate/Undergraduate Equivalency: BIOC 455.
 

BIOC 560 - CANCER BIOLOGY

Long Title: CANCER BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Provides an integrated lecture series summarizing current knowledge in cancer biology and integrating current literature with basic concepts. Topics include: statistics of incidence/survival, types of cancer, pathology, the process of carcinogenesis and sources of carcinogens, genetic and epigenetic mechanisms and consequences, cancer progression, metastasis and current treatment options. Students will learn to use online databases to develop independent strategies for analyzing datasets. There will be several writing assignments and in class oral presentations of research articles. This course requires instructor permission to enroll. Please fill out the special registration form from https://registrar.rice.edu/student/special_registration. All requests will be reviewed and you will be notified of an enrollment decision. Instructor Permission Required.Cross-list: BIOE 560, Graduate/Undergraduate Equivalency: BIOC 460. Mutually Exclusive: Credit cannot be earned for BIOC 560 and BIOC 460.
 

BIOC 563 - ENDOCRINOLOGY

Long Title: ENDOCRINOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 201 AND BIOC 301
Description: Study of the action of mammalian hormones in terms of whole organismal physiological responses and intracellular molecular signaling pathways. Restricted to students in the Professional Science Masters Program, (MS BioSci Res & Health Policy). Graduate/Undergraduate Equivalency: BIOC 463. Mutually Exclusive: Credit cannot be earned for BIOC 563 and BIOC 463.
 

BIOC 570 - COMPUTATION WITH BIOL DATA

Long Title: COMPUTATION WITH BIOLOGICAL DATA
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: This course will teach programming and analysis techniques essential for modern research in the biological sciences. Students will learn the basics of programming in the MATLAB or Python scripting languages and applications to analyzing biological data. There will be a particular focus on quantitative image and sequence analysis. Instructor Permission Required.Graduate/Undergraduate Equivalency: BIOC 470. Mutually Exclusive: Credit cannot be earned for BIOC 570 and BIOC 470.
 

BIOC 571 - BIOINFORMATICS: SEQUENCE

Long Title: BIOINFORMATICS: SEQUENCE ANALYSIS
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Pairwise and multiple sequence alignment, Markov chains and HMMs, Phylogenetic reconstruction, Haplotype inference, Computational models of RNA structure, Gene finding, Genome rearrangements, and comparative genomics. Cross-list: COMP 571.
Course URL: http://www.cs.rice.edu/~nakhleh/COMP571/
 

BIOC 572 - BIOINFORMATICS: NETWORKS

Long Title: BIOINFORMATICS: NETWORK ANALYSIS
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: This course covers computational aspects of biological network analysis, a major theme in the area of systems biology. The course addresses protein-protein interaction networks, signaling, and metabolic networks, and covers issues related to reconstructing, analyzing, and integrating various types of networks. Cross-list: BIOE 564, COMP 572.
Course URL: http://www.cs.rice.edu/~nakhleh/COMP572/
 

BIOC 573 - IMMUNOLOGY

Long Title: IMMUNOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Prerequisite(s): BIOC 201
Description: Cellular and molecular basis of innate and adaptive immune function in mammals. Graduate students will be required to do all the usual assignments associated with the undergraduate section of the course but in addition will write a substantial paper on some aspects of the field that is relevant to their planned careers in biomedical research/biotechnology. Graduate/Undergraduate Equivalency: BIOC 372. Recommended Prerequisitie(s): BIOC 301 AND BIOC 341. Mutually Exclusive: Credit cannot be earned for BIOC 573 and BIOC 372.
 

BIOC 575 - INTRODUCTION TO RESEARCH

Long Title: INTRODUCTION TO RESEARCH
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Seminar
Credit Hours: 1
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Introduction of first-year graduate students to the research programs and laboratories of individual faculty members. Open only to BCB graduate students.
 

BIOC 576 - FOUNDATIONS OF BIOTECHNOLOGY

Long Title: FOUNDATIONS OF BIOTECHNOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Seminar
Credit Hours: 1
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Graduate level introduction to a wide range of research methods in biosciences and bioengineering. Individual faculty members from the Biosciences and Bioengineering will each present practices and techniques for their areas of expertise. A web-based methods database will be constructed, with student involvement, from the library of lectures. Cross-list: BIOE 576.
 

BIOC 577 - FOUNDATIONS OF BIOTECHNOLOGY

Long Title: FOUNDATIONS OF BIOTECHNOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Seminar
Credit Hours: 1
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Graduate level introduction to a wide range of research methods in biosciences and bioengineering. Individual faculty members from the biosciences and bioengineering will each present practices and techniques for their areas of expertise. A web-based methods database will be constructed, with student involvement, from the library of lectures. Cross-list: BIOE 577.
 

BIOC 578 - BIOTECHNOLOGY PRACTICUM

Long Title: BIOTECHNOLOGY PRACTICUM
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Internship/Practicum
Credit Hours: 1
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: This course is part of the NIH Biotechnology Training Program and is limited to program participants. Students will receive exposure and training in cutting edge concepts and technologies. Cross-list: BIOE 578.
 

BIOC 580 - PROTEIN ENGINEERING

Long Title: PROTEIN ENGINEERING
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Manipulation of gene expression in prokaryotic and eukaryotic cells. Rational design and directed solutions for cell and protein engineering. Selection and screening technologies and process optimization. Synthetic Biology: engineering and application of gene circuits. Molecular biotechnology applications: Diagnosis, Therapeutics and Vaccines. Cross-list: BIOE 580, CHBE 580. CHBE 310/510 or equivalent is highly recommended.
 

BIOC 581 - GRAD SEM BIOCHEM & CELL BIOL

Long Title: GRADUATE SEMINAR IN BIOCHEMISTRY AND CELL BIOLOGY
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Seminar
Credit Hours: 1
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: A discussion of selected research topics. Required of all Biochemistry and Cell Biology graduate students. Open only to BCB graduate students. Repeatable for Credit.
 

BIOC 582 - GRAD SEM/BIOCHEM & CELL BIOL

Long Title: GRADUATE SEMINAR IN BIOCHEMISTRY AND CELL BIOLOGY
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Seminar
Credit Hours: 1
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: A discussion of selected research topics. Required of all Biochemistry and Cell Biology graduate students. Open only to BCB graduate students. Repeatable for Credit.
 

BIOC 583 - MOLECULAR INTERACTIONS

Long Title: MOLECULAR INTERACTIONS
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Seminar
Credit Hours: 4
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Must be enrolled in one of the following Major(s):
Biochemistry and Cell Biology
Description: First of two integrated classes taken by first-year graduate students in BCB (to be followed by BIOC 588, Cellular Interactions). Covers advanced topics in biochemistry, ranging from protein and nucleic acid synthesis, folding, function, and engineering to allostery, dynamics, and degradation with an emphasis on fundamental principles, research methodologies, problem solving, and critical analysis of primary literature. Enrollment limited to BCB graduate students. Open only to BCB graduate students.
 

BIOC 585 - FUNDAMENTALS OF NEUROSCIENCE

Long Title: FUNDAMENTALS OF CELLULAR AND MOLECULAR NEUROSCIENCE
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Cellular, molecular, and integrative mechanisms of neural function, including membrane and axon physiology, synaptic transmission and plasticity, sensory transduction and processing. Graduate/Undergraduate Equivalency: BIOC 385. Recommended Prerequisite(s): BIOC 201. Mutually Exclusive: Credit cannot be earned for BIOC 585 and BIOC 385.
 

BIOC 587 - PROPOSAL WRITING

Long Title: RESEARCH DESIGN, PROPOSAL WRITING, AND PROFESSIONAL DEVELOPMENT
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Seminar
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Preparation for professional scientific communication with an emphasis on writing research proposals, describing work in progress, and presenting data in context of research goals. Open only to BCB graduate students.
 

BIOC 588 - CELLULAR INTERACTIONS

Long Title: CELLULAR INTERACTIONS
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Seminar
Credit Hours: 4
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Must be enrolled in one of the following Major(s):
Biochemistry and Cell Biology
Description: Second of two integrated classes taken by first-year graduate students in BCB (following BIOC 583, Molecular Interactions). Covers advanced topics in genetics, cell biology, and developmental biology, focusing on cellular, tissue, and organismal structure and function with an emphasis on fundamental principles, research methodologies, and critical analysis of primary literature.
 

BIOC 589 - COMP MOLECULAR BIOENG/BIOPHYS

Long Title: COMPUTATIONAL MOLECULAR BIOENGINEERING/BIOPHYSICS
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: This is a course designed for students in computationally-oriented biomedical and bioengineering majors to introduce the principles and methods used for the simulations and modeling of macromolecules of biological interest. Protein conformation and dynamics are emphasized. Empirical energy function and molecular dynamics calculations, as well as other approaches, are described. Specific biological problems are discussed to illustrate the methodology. Cross-list: BIOE 589. Recommended Prerequisite(s): MATH 212, BIOC 301, BIOE 332.
 

BIOC 590 - SPEC TOPCS BIOCHEM&CELL BIO

Long Title: SPECIAL TOPICS IN BIOCHEMISTRY AND CELL BIOLOGY
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Seminar
Credit Hours: 1
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Development of specific topic areas at the graduate level. Instructor Permission Required.
 

BIOC 592 - TOPICS QUANT BIO & BIOMED INFO

Long Title: TOPICS IN QUANTITATIVE BIOLOGY AND BIOMEDICAL INFORMATICS (KECK SEMINAR)
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Seminar
Credit Hours: 1
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: A discussion of selected research topics in quantitative biology and biomedical informatics. Cross-list: KECK 592. Repeatable for Credit.
 

BIOC 593 - TOPICS IN PLANT BIOLOGY

Long Title: CURRENT TOPICS IN PLANT BIOLOGY
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Seminar
Credit Hours: 1
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Must be enrolled in one of the following Major(s):
Biochemistry and Cell Biology
Description: Discussion of selected research topics in current plant biology literature. Repeatable for Credit.
 

BIOC 599 - GRADUATE TEACHING IN BIOCHEM

Long Title: GRADUATE TEACHING IN BIOCHEMISTRY AND CELL BIOLOGY
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Independent Study
Credit Hours: 1
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Must be enrolled in one of the following Major(s):
Biochemistry and Cell Biology
Description: Supervised instruction in teaching biochemistry and cell biology. Repeatable for Credit.
 

BIOC 611 - RESEARCH SEMINAR

Long Title: RESEARCH SEMINAR IN BIOCHEMISTRY AND CELL BIOLOGY
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Seminar
Credit Hours: 1
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Discussion of individual research or current topics in particular areas. Intended for students conducting research projects in the lab of the instructor. Repeatable for Credit.
 

BIOC 643 - MECHANOTRANSDUCTION

Long Title: CELL MECHANICS, MECHANOTRANSDUCTION AND THE CELL MICROENVIRONMENT
Department: Biosciences
Grade Mode: Standard Letter
Course Type: Lecture
Credit Hours: 3
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Mechanotransduction is a fundamental process essential for living systems and plays a fundamental role in cell signaling, cancer metastasis and stem cell differentiation. Additionally, fundamental biological processes such as endocytosis cell fusion and cell migration are driven by a coordinated interplay of molecular interactions that drive membrane deformation. This course will survey the current understanding of mechanotransduction and the mechanical properties of cells and their microenvironment, including membrane and cytoskeletal mechanics. Experimental approaches for measuring and manipulating the material properties of cells and their environment; including optical, electrical and magnetic techniques will be covered. A variety of application will be covered, including manipulation in engineering of mechanotransduction pathways to drive cell migration and stem cell differentiation. Instructor Permission Required.Cross-list: BIOE 643, PHYS 643.
 

BIOC 701 - GRADUATE LAB RESEARCH I

Long Title: GRADUATE LAB RESEARCH I
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Research
Credit Hours: 2 TO 4
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Graduate research in Biochemistry and Cell Biology. Designed for short term laboratory projects for first year graduate students. Recommended prerequisite(s): Graduate standing in Biochemistry and Cell Biology. Repeatable for Credit.
 

BIOC 702 - GRADUATE LAB RESEARCH II

Long Title: GRADUATE LAB RESEARCH II
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Research
Credit Hours: 2 TO 4
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Description: Graduate research in Biochemistry and Cell Biology. Designed for short term laboratory projects for first year graduate students. Recommended prerequisite(s): Graduate standing in Biochemistry and Cell Biology. Repeatable for Credit.
 

BIOC 800 - BCB GRADUATE RESEARCH

Long Title: BIOCHEMISTRY & CELL BIOLOGY GRADUATE RESEARCH
Department: Biosciences
Grade Mode: Satisfactory/Unsatisfactory
Course Type: Research
Credit Hours: 1 TO 15
Restrictions:
Must be enrolled in one of the following Level(s):
Graduate
Must be enrolled in one of the following Major(s):
Biochemistry and Cell Biology
Description:  Repeatable for Credit.