Course Schedule and Catalog

Long Title: ENVIRONMENTAL CRISIS SEMINAR

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Distribution Group: Distribution Group III

Credit Hours: 1

Description: Seminar topics may vary.

Long Title: FRESHMAN SEMINAR ON LOCAL BIOLOGY RESEARCH

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 1

Description: A 5-week seminar course to introduce freshmen prospective biologists to the excitement of research at Rice and the Medical Center and to provide context with which to think about facts presented in biosciences textbooks. Small groups will meet weekly with a graduate student or postdoctoral researcher to explore a published research article by a local lab, gaining background information about the subject and exposure to the research techniques. In the final session, the group will tour the lab that produced the featured article. Additional tours and activities TBA. All first-year students are eligible to enroll in BIOS 115 regardless of AP credit. This course meets in the second half of the semester.

Long Title: FUNDAMENTAL CONCEPTS IN BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Description: Biological topics of current interest, covering advances in biotechnology, human health, agriculture, and the environment. Topics focus on the underlying biology, but may also include the social/political/economic impact. Each session is taught by an expert in that field with the assistance of a class coordinator.

Long Title: INTRODUCTORY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Description: The first in an integrated sequence of four courses (BIOS 201, 202, 301, 302). Chemistry and energetics, cell physiology, cell biology, Mendelian genetics, molecular genetics, developmental biology, and plant physiology.

Long Title: INTRODUCTORY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Prerequisite(s): BIOS 201

Description: The second in an integrated sequence of four courses (BIOS 201, 202, 301, 302). Molecular genetics, DNA technology, antibiotics and antivirals, animal behavior, evolution, ecology, diversity, and conservation biology.

Long Title: ENVIRONMENTAL SUSTAINABILITY: THE DESIGN & PRACTICE OF COMMUNITY AGRICULTURE

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture/Laboratory

Credit Hours: 1

Description: The course introduces the fundamentals of community garden design and practice. Responsibilities will center on developing and improving the Rice Community Garden. The semester will begin with a short series of lectures by successful growers from the Houston community. A strong emphasis will be on learning and applying ecological principles to the practice of community agriculture. Repeatable for Credit.

Long Title: INTRODUCTION TO EXPERIMENTAL BIOSCIENCES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory, Lecture

Credit Hours: 2

Prerequisite(s): BIOS 201

Description: Introduction to "laboratory math," record keeping, technical communication, selected research strategies, and methods of science, in a biological context. Taught in the first half of each semester. *** Special Registration Instructions: To register, go to the course URL, select "Getting Started" then "Register" and follow instructions from there. Instructor Permission Required. ***SPECIAL REGISTRATION REQUIRED*** The course is available but is closed to registration through ESTHER. To register, go to the course URL, select "Getting started" then "Register" and follow instructions from there.

Long Title: INTRO LAB MOD ECOLOGY AND EVOLUTIONARY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Description: Experimental, laboratory, and field studies of natural history, ecology, evolution, and animal behavior. Computer simulations of population genetics. Course will begin after mid-semester break in the Fall semester and after mid-term recess in the Spring semester.

Long Title: BIOCHEMISTRY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): CHEM 211

Description: The third in an integrated sequence of four courses (BIOS 201, 202, 301, 302). Structure and function of proteins, enzymes, and nucleic acids; enzyme kinetics; glycolysis, aerobic metabolism, and energy coupling. Recommended prerequisite(s): CHEM 212

Long Title: BIOCHEMISTRY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 301 AND CHEM 211

Description: The final in an integrated sequence of four courses (BIOS 201, 202, 301, 302). Introduction to metabolism, membranes, electron transport, oxidative phosphorylation, and regulation. Biosciences Group A. Recommended prerequisite(s): CHEM 212.

Long Title: INDEPENDENT STUDY FOR ECOLOGY & EVOLUTIONARY BIOLOGY UNDERGRADUATES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1 TO 4

Prerequisite(s): BIOS 211

Description: Program of independent study for students with previous training in the biosciences. Includes a research paper. Students are expected to spend at least three hours per week in the laboratory for each semester hour of credit. If taken for two or more hours, counts as one required lab course but not as a Group A or Group B course. If receiving two or more credits, students will be required to particpate in the university annual undergraduate symposium in the spring semesters. Instructor Permission Required. Repeatable for Credit.

Long Title: GENETICS: SCIENCE AND SOCIETY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: The course uses an interdisciplinary perspective. The course will cover biological basics of genes, DNA, and sequencing techniques; cultural and historical aspects to genetics, including essentialism and eugenics and policy issues. Cross-list: ANTH 314.

Long Title: ADVANCED MODULES IN PLANT BIOCHEMISTRY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Prerequisite(s): CHEM 211 OR BIOS 311

Description: Bio-organic lab module combining molecular biology to express plant terpene synthases in microbial systems with product structural analysis using GC-MS and NMR. Final lab reports will be in the format of a scientific publication. Cross-listed with CHEM 378. Instructor Permission Required.

Long Title: SEMINAR IN RESEARCH METHODOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Independent Study

Credit Hours: 2

Description: A course based on laboratory research done outside the university which will use seminars, discussion and papers to develop communication skills in research. Instructor Permission Required. Repeatable for Credit.

Long Title: INDEPENDENT RESEARCH FOR BIOCHEMISTRY AND CELL BIOLOGY UNDERGRADUATES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Research

Credit Hours: 1 TO 4

Prerequisite(s): BIOS 211

Description: Independent research in Rice BCB faculty laboratories (section 1) or in a non-BCB lab at Rice (section 2). In the summer term, students spend at least 42 hours in lab per hour of credit over the 8 week General Session (5.25 hours/week/credit hour). If taken for 3 or more hours, counts as one required lab course but not as a Group A or Group B course. Requires a proposal abstract, weekly reports, and a research paper. Students wishing to take BIOS 310 for up to seven credits in the summer may enroll in a second BIOS 310 section for up to 3 credits. Section 1 students may add section 3 and section 2 students may add section 4. NOTE: Off-campus labs do not qualify as sites for BIOS 310 during the summer session. Instructor Permission Required. Recommended: Instructor permission. Repeatable for Credit.

Long Title: ADVANCED EXPERIMENTAL BIOSCIENCES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture/Laboratory

Credit Hours: 1

Prerequisite(s): BIOS 211 AND BIOS 301

Description: Advancement of basic laboratory, record keeping, and technical communication skills. Taught first half of each semester. NOTICE: The course is closed to registration on Esther. To register, you must obtain the instructor's signature on a Special Registration form available from the Office of the Registrar. Instructor Permission Required.

Long Title: EXPERIMENTAL MOLECULAR BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Prerequisite(s): BIOS 311

Description: Introduction to strategies in molecular biology and experience in preparation of a scientific poster. Taught first half of spring or second half of fall semester. NOTICE: The course is closed to registration on Esther; to register, you must get the instructor's signature on a Special Registration form available from the Office of the Registrar. Instructor Permission Required.

Long Title: ADVANCED EXPERIMENTAL MOLECULAR BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Prerequisite(s): BIOS 311 AND BIOS 312

Description: Team projects using microarrays to analyze gene expression; teams give a PowerPoint presentation to communicate their findings. Taught second half of spring semester. NOTICE: the course is closed to registration on Esther. To register, you must obtain the instructor's signature on a Special Registration form available from the Office of the Registrar. Instructor Permission Required.

Long Title: EXPERIMENTAL CELL BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Prerequisite(s): BIOS 301 AND BIOS 311 AND BIOS 341

Description: Application of transmission electron microscopy to research in cell biology. Students will interview a faculty investigator and conduct an original research project. Recommended for students interested in a research career. Instructor Permission Required.

Long Title: EXPERIMENTAL PHYSIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Prerequisite(s): BIOS 301 AND BIOS 311

Description: An instrumentation-intensive short course in membrane electrophysiology and vertebrate nerve and muscle physiology. Research reports require interpretation of laboratory data in terms of concepts at the molecular level. Starts the second half of the semester.

Long Title: LAB MODULE IN ECOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Prerequisite(s): BIOS 323 OR BIOS 325 or permission of instructor

Description: Field and lab experiments in ecology.

Long Title: LAB MODULE IN BEHAVIOR

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Prerequisite(s): BIOS 321 AND BIOS 213

Description: Field experiments in behavior. Learn to formulate and test hypotheses on bird behavior using mockingbirds, grackles, and herons nesting on campus. Instructor Permission Required.

Long Title: LABORATORY STUDIES IN APPLIED MICROBIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Prerequisite(s): BIOS 311

Description: Microbiological analysis of water, isolation, culture, observation, assay, and identification of bacteria, in the context of a simulated internship with a water/public health department. Starts the second half of the semester, self-scheduled after the first four formal meetings. Requires daily attention to cultures during the week.

Long Title: LABORATORY IN TISSUE CULTURE

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Prerequisite(s): BIOS 211 OR CHEM 214

Description: Introduction to tissue culture techniques, including cell passage, cell attachment and proliferation assays, and a transfection assay. Sections 1 and 2 are taught during the first half of the semester. Sections 3 and 4 are taught during the second half of the semester. Your registration for this course will not be accepted until you obtain Dr. Saterbak's signature on an Undergraduate Special Registration Request Form. Instructor Permission Required.Cross-list: BIOE 342.

Long Title: ANIMAL BEHAVIOR

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Prerequisite(s): BIOS 201 OR BIOS 202

Description: Evolutionary theory is used to evaluate behavioral adaptations of organisms to their environment. Biosciences Group B.

Long Title: CONSERVATION BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202 or permission of instructor

Description: The course is designed to give students a broad overview of conservation biology. Lecture and discussions will focus on conservation issues such as biodiversity, extinction, management, sustained yield, invasive species and preserve design. Biosciences Group B. Cross-list: ENST 323.

Long Title: ECOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202 or permission of instructor

Description: Study of population dynamics, species interactions, plant and animal comunity organization, and ecosystem function. Biosciences Group B.

Long Title: INSECT BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202 or permission of instructor

Description: This course addresses contemporary issues in ecology and evolution through the lens of insect diversity. Laboratory and field exercises provide hands-on experience with collection and curation of insect specimens. Readings span a broad literature (popular to technical). Writing and oral reports develop proficiency in scientific communication. 1 credit lab is required (BIOS 330). Biosciences Group B.

Long Title: BIOLOGICAL DIVERSITY LABORATORY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Prerequisite(s): BIOS 201 AND BIOS 202 AND BIOS 213

Description: The course will examine (1) measures of biological diversity (taxic, molecular, and phylogenetic); (2) the ecological and evolutionary causes of biological diversity; (3) issues regarding the contribution of biological diversity to ecosystem function. A primary emphasis will be placed on experimental design and the measurement and estimation of biological diversity. Possible problems associated with the measurement and estimation of biological diversity will also be discussed. The course will take form of weekly preparatory meetings and culminate in a three-day exercise (taking place over fall break) at a field site in Texas where student will be responsible for designing and carrying out a study examining some aspect of biological diversity (taxic or functional group) with respect to such variables as habitat diversity, disturbance rate, or productivity. The course will emphasize oral presentations and written "publication" format papers.

Long Title: EVOLUTION OF GENES & GENOMES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202

Description: The course provides an overview of the evolution of genes and genomes. Using many examples, the course introduces databases and the Worldwide Web, and molecular and statistical methods used to study the evolution of genes and genomes. Broad-scale evolutionary patterns and medical applications based on genome analyses are presented. Biosciences Group B.

Long Title: ANIMAL BIOLOGY AND PHYSIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Prerequisite(s): BIOS 201 OR BIOS 202 or permission of instructor

Description: The evolution and systematics of the animal kingdom with consideration of functional anatomy, comparative physiology, behavior, medical implications and resource management. Biosciences Group B.

Long Title: INSECT BIOLOGY LAB

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Prerequisite(s): BIOS 201 AND BIOS 202 or permission of instructor

Description: Required lab for BIOS 326.

Long Title: FUNDAMENTALS OF SYSTEMS PHYSIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND MATH 211

Description: This course will teach the fundamentals of physiology at the organism, tissue, and cellular levels. Emphasis will be on engineering aspects of physiology. This course includes several projects and written assignments. Biosciences Group A. Cross-list: BIOE 322.

Long Title: EVOLUTION

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Prerequisite(s): BIOS 202 or permission of instructor

Description: Principles of biological evolution. Topics include natural selection, adaptation, molecular evolution, formation of new species, the fossil record, biogeography, and principles of classification. Biosciences Group B.

Long Title: PLANT DIVERSITY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Prerequisite(s): BIOS 202

Description: The evolution, systematics, and ecology of plants, with emphasis on flowering plants and biodiversity. Biosciences Group B.

Long Title: FIELD BIRD BIOLOGY LAB

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Description: This course centers on a series of five field trips to diverse habitats for observing birds both immigrants and residents. Each will be preceded by a lecture and students will do two projects.

Long Title: DESIGN AND ANALYSIS OF BIOLOGICAL EXPERIMENTS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: This course will address methods to set up biological experiments in order to maximize the ability to draw meaningful statistical conclusions. We will discuss factorial, nested, split-plot, and repeated-measures designs, as well as analysis of the data and interpretation of the results. The course also includes analysis of undesigned (observational) data sets. The course is not an introduction to statistics, but it will include a brief review of basic statistics. An interactive statistical-software package will be used throughout for class demos, homework assignments, and a class project. Data sets from many areas of biology will be used.

Long Title: BIOMETRY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): STAT 280 OR STAT 305 OR ESCI 451 OR BIOS 338

Description: This course provides advanced training in statistical analysis in ecology and evolutionary biology. Working with real data sets, we will explore diverse topics including breeding designs and quantitative genetics analysis, multiple regression, path analysis, structural equation modeling, bootstrapping and randomization tests, and nonmetric multidimensional scaling. Biosciences Group B.

Long Title: GLOBAL BIOGEOCHEMICAL CYCLES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Description: This course introduces students to the coupled nature of the biosphere, atmosphere and hydrosphere using as focal points elemental cycles such as those of carbon and nitrogen. Biosciences Group B. Cross-list: ENST 340, ESCI 340.

Long Title: CELL BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Distribution Group: Distribution Group III

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202

Description: Molecular mechanisms of the processes common to all cells, including exposition of structure, function, and biogenesis of all subcellular organelles. Emphasis will be on cytoplasmic events; molecular studies of transcription will be taught in BIOS 344. Biosciences Group A.

Long Title: MOLECULAR BIOLOGY AND GENETICS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: Mendelian genetics, population genetics, mapping, gene expression and regulation, genetic engineering, DNA replication and recombination, human genetics, genetic disease and gene therapy. Biosciences Group A. Recommended Prerequisite(s): BIOS 201 and BIOS 202.

Long Title: PHYSICAL CHEMISTRY FOR THE BIOSCIENCES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): CHEM 211 AND CHEM 212 AND PHYS 125 AND PHYS 126 AND BIOS 301

Description: Study of selected aspects of physical chemistry as it relates to the biosciences. Includes thermodynamics, reaction rate theory, quantum mechanics, and atomic and molecular structure. Biosciences Group A.

Long Title: METABOLIC ENGINEERING FOR GLOBAL HEALTH ENVIRONMENTS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOE 260 AND PHYS 126 AND MATH 102

Description: Importance of nutritional and pharmaceutical compounds, impact of cost of compounds on global health; Overview of biochemical pathways; Genetic engineering and molecular biology tools for ME; Nutritional molecules; Pharmaceuticals (antibiotics, tamiflu-against influenza virus; anti-parasite compounds against malaria and filaria diseases; anti-diarrhea treatments).

Long Title: BIOENGINEERING FOR GLOBAL HEALTH ENVIRONMENTS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOE 260 AND PHYS 126 AND MATH 102

Description: Clinical trial design, regulation of medical technologies, medical technology assessment. Detailed case studies of vaccine development, diagnostic tests, cancer screening.

Long Title: TRANSFER CREDIT IN BIOCHEMISTRY AND CELL BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: For transfer of courses which have no current equivalent in the Rice curriculum, but which can be counted as Group A Biosciences courses in satisfying requirements for majors in Biosciences. Biosciences Group A. Repeatable for Credit.

Long Title: TRANSFER CREDIT IN ECOLOGY AND EVOLUTIONARY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: For transfer of courses which have no current equivalent in the Rice curriculum, but which can be counted as Group B Biosciences courses in satisfying requirements for majors in the Biosciences. Biosciences Group B. Repeatable for Credit.

Long Title: LABORATORY TRANSFER CREDIT IN BIOSCIENCES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Description: For transfer of an advanced laboratory course in the biosciences that has no current equivalent in the Rice Biosciences curriculum. Any student may receive a maximum of 1 credit of BIOS 393.

Long Title: UNDERGRADUATE HONORS RESEARCH

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Research

Credit Hours: 5

Prerequisite(s): BIOS 201 AND BIOS 202 AND BIOS 301

Description: Open only to undergraduate majors who meet specific requirements and with the permission of the research supervisor and chair. Registration for BIOS 401 implies a commitment to participate in research for at least 2 semesters. A substantial written report of the research work is required. A substantial written report of the research work is required. For those taking 401 and 402 in the same academic year, the student thesis report is due at the end of the second term, the spring BIOS 402 term. Biosciences Group A. Department Permission Required. Repeatable for Credit.

Long Title: UNDERGRADUATE HONORS RESEARCH

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Research

Credit Hours: 5

Prerequisite(s): BIOS 201 AND BIOS 202 AND BIOS 301

Description: See BIOS 401. Biosciences Group A. Department Permission Required. Repeatable for Credit.

Long Title: UNDERGRADUATE HONORS RESEARCH IN ECOLOGY AND EVOLUTIONARY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Research

Credit Hours: 5

Description: Open only to undergraduate majors who meet specific requirements and with permission of the research supervisor and chair. Registration for BIOS 403/404 implies a commitment to participate in research for at least 2 semesters. Department Permission Required.

Long Title: UNDERGRADUATE HONORS RESEARCH IN ECOLOGY AND EVOLUTIONARY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Research

Credit Hours: 5

Description: See BIOS 403. Instructor Permission Required.

Long Title: INDEPENDENT RESEARCH/INTERNSHIP PROGRAM

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Independent Study

Credit Hours: 0

Description: This independent research course offers multi-disciplinary training in the area of cellular engineering within the Departments of Bioengineering and Biochemistry and Cell Biology. Areas of research will include engineering of hard and soft tissue formation, cardiovascular tissue engineering, engineering cell surface interactions regulating movement and metabolic engineering. Students will conduct independent research under the supervision of a faculty mentor.

Long Title: UNDERGRADUATE RESEARCH SEMINAR

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 1

Description: Discussion of current research in the area under investigation. A substantial written report of the BIOS 401/402 is required. Department Permission Required. Repeatable for Credit.

Long Title: NEUROBIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202 AND BIOS 301

Description: Cellular and molecular mechanisms of nervous system function. Emphasis on membrane and synaptic biophysics, sensory and motor systems, neuronal plasticity, and development. Open to juniors and seniors. Biosciences Group A.

Long Title: ENDOCRINOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202 AND BIOS 301 AND BIOS 341

Description: Study of the molecular and cellular mechanisms of hormone synthesis and of target cell responses. Study of the role of hormone action in mammalian physiological responses. Biosciences Group A.

Long Title: IMMUNOBIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202

Description: Cellular and molecular basis of immune function in mammals. Biosciences Group A. Recommended prerequisite(s): BIOS 301 or BIOS 341.

Long Title: MICROBIOLOGY AND BIOTECHNOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202 AND BIOS 301 or permission of instructor

Description: Structure and functions of microorganisms with emphasis on their environmental, industrial and medical importance. Biosciences Group A.

Long Title: PLANT MOLECULAR GENETICS AND DEVELOPMENT

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 301 AND BIOS 341 or permission of instructor

Description: Novel aspects of plant biology and development with emphasis on molecular and genetic mechanisms. Plant responses to the environment and the use of bioengineering and other means to develop new plant products will also be covered. Biosciences Group A. Graduate/Undergraduate Equivalency: BIOS 525.

Long Title: ADVANCED EVOLUTIONARY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202 AND (BIOS 334 OR BIOS 321)

Description: Develop a critical understanding of evolutionary theory through lectures and discussion across a wide range of evolutionary topics. With the instructor's help, students will use current papers to stimulate debate on the theories, philosophies and methods of the study of evolution. Biosciences Group B.

Long Title: ADVANCED ECOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202 AND BIOS 325 or permission of instructor

Description: Students will develop a critical understanding of the discipline of ecology through a combination of lectures and discussion that span a range of topics. With the instructor's help, students will use current papers to stimulate debate on the theories, philosophies and methods of the study of populations, communities, and ecosystems. Biosciences Group B.

Long Title: ENZYME MECHANISMS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): CHEM 212

Description: Enzymology is a biological extension of organic chemistry. This course will survey examples of enzyme-catalyzed reactions with emphasis on mechanisms. Enzymes that use catalytic cofactors (vitamins) will be covered, as will those that rely on amino acid side chains. Biosciences Group A. Cross-list: CHEM 440.

Long Title: DEVELOPMENT

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202 AND BIOS 341 or permission of instructor

Description: Analysis of the processes and principles of development as seen in a broad spectrum of eukaryotic organisms. Biosciences Group A.

Long Title: ADVANCED MOLECULAR BIOLOGY AND GENETICS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202 AND BIOS 301 AND BIOS 344

Description: Molecular and genetic aspects of the regulation of gene expression as seen in simple prokaryotic systems and the model eukaryotic systems used for studies of development. Biosciences Group A.

Long Title: EXTRACELLULAR MATRIX

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: This course will address the biology, orgnization, mechanics, and turnover of extracellular matrix. There will be an emphasis on cells and cell-matrix interactions, matrix distributions in connective tissues and organs, techniques for measurement and modeling, changes with growth and aging, and tissue/matrix degradation including enzyne kinectics. Biosciences Group A. Cross-list: BIOE 464.

Long Title: MOLECULAR BIOPHYSICS I

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 301 AND BIOS 352 or permission of instructor

Description: Focus on principles of common biophysical methods used for study of conformations and dynamics of biological macromolecules and assemblies. Topics cover spectroscopic methods (absorption, fluorescence, circular dichroism, epr, NMR), transport processes, sedimentation, calorimetry, mass spectrometry, crystallography, cryo-electron microscopy, atomic force microscopy, ligand-protein interactions, protein folding, single molecule detection, computer simulations, functional genomics and laboratory evolution. Biological examples will be used to demonstrate merits and complementarity in each of the biophysical methods. Biosciences Group A. Graduate/Undergraduate Equivalency: BIOS 551.

Long Title: MOLECULAR BIOPHYSICS II

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: Advanced treatment of X-ray crystallography, NMR spectroscopy, and electron microscopy. Emphasis on theory and application of these methods for the determination of the three-dimensional structure and dynamics of biological molecules and complexes. Biosciences Group A. Graduate/Undergraduate Equivalency: BIOS 552. Recommended prerequisite(s): BIOS 301, BIOS 352, BIOS 481, working knowledge of a programming language such as Fortran, C, Basic, MATLAB, or Pascal.

Long Title: ADVANCED CELL BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 3

Description: Review of literature on current biosciences research, with emphasis on human diseases, their treatment, and drug discovery. Biosciences Group A. Graduate/Undergraduate Equivalency: BIOS 588.

Long Title: PLANT MOLECULAR GENETICS AND DEVELOPMENT

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 301 AND BIOS 341

Description: Novel aspects of plant biology and development with emphasis on molecular and genetic mechanisms. Plant responses to the environment and the use of bioengineering and other means to develop new plant products will also be covered. Graduate/Undergraduate Equivalency: BIOS 425.

Long Title: LAB MODULE IN NMR SPECTROSCOPY AND MOLECULAR MODELING

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 2

Prerequisite(s): BIOS 352 or permission of instructor

Description: The students will learn to set up, acquire, and process one-dimensional and basic two-dimensional NMR experiments. Spectral interpretation (resonance assignment and extraction of structural information) for nucleic acids and proteins using homonuclear and heteronuclear data will be performed. Enrollment limited to 12, with priority to graduate students. Offered first half of the semester.

Long Title: LABORATORY MODULE IN OPTICAL SPECTROSCOPY AND KINETICS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 2

Description: Students learn the principles behind fluorescence, circular dichroism, analytical ultracentrifugation, spectroscopy and rapid kinetics by carrying out experiments with genetically engineered proteins and state-of-the-art equipment. Data will be interpreted and manipulated using curve-fitting and graphics software. Offered second half of the semester. Recommended Prerequisite(s): BIOS 352 or equivalent. Concurrent or previous enrollment in BIOS 481 or BIOS 551.

Long Title: BIOINFORMATICS & COMPUTATIONAL BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 2

Description: An introduction to the emerging field of bioinformatics. A series of lectures, combined with hands-on exercises. The topics to be discussed include sequence comparison, structure analysis, phylogenetics, database searching, microarrays and proteomics. Recommended prerequisite(s): BIOS 301 or permission of instructor.

Long Title: PRACTICAL X-RAY CRYSTALLOGRAPHY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture/Laboratory

Credit Hours: 2

Prerequisite(s): BIOS 481 OR BIOS 551

Description: This is an introduction to macromolecular crystallography with emphasis on crystallization methods, data acquisition, processing and molecular model-building. Approaches to solving structures will be discussed, as well as refinement of molecular models. Offered second half of the semester.

Long Title: SPECIAL TOPICS IN ECOLOGY AND EVOLUTIONARY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Research

Credit Hours: 1

Description:  Repeatable for Credit.

Long Title: SPECIAL TOPICS IN ECOLOGY AND EVOLUTIONARY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 1

Description:  Repeatable for Credit.

Long Title: SECONDARY METABOLISM

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): CHEM 212

Description: A survey of the biosynthetic pathways leading to the major classes of natural products. Topics covered include the use of radioactive and stable isotopes, the synthesis of labeled organic compounds, mechanistic investigations of secondary metabolic enzymes, and the cloning and characterization of secondary metabolic genes. Biosciences Group A. Cross-list: CHEM 543.

Long Title: DEVELOPMENT

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202 AND BIOS 301 AND BIOS 341 or permission of instructor

Description: Analysis of the processes and principles of development as seen in a broad spectrum of eukaryotic organisms. Biosciences Group A.

Long Title: ADVANCED MOLECULAR BIOLOGY AND GENETICS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND BIOS 202 AND BIOS 301 AND BIOS 344

Description: Molecular and genetic aspects of the regulation of gene expression as seen in simple prokaryotic systems and the model eukaryotic systems used for studies of development.

Long Title: MOLECULAR BIOPHYSICS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 301 AND BIOS 352 or permission of instructor

Description: Focus on principles of common biophysical methods used for study of conformations and dynamics of biological macromolecules and assemblies. Topics cover spectroscopic methods (absorption, fluorescence, circular dichroism, epr, NMR), transport processes, sedimentation, calorimetry, mass spectrometry, crystallography, cryo-electron microscopy, atomic force microscopy, ligand-protein interactions, protein folding, single molecule detection, computer simulations, functional genomics and laboratory evolution. Biological examples will be used to demonstrate merits and complementarity in each of the biophysical methhods. Graduate/Undergraduate Equivalency: BIOS 481.

Long Title: MOLECULAR BIOPHYSICS II

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: Advanced treatment of X-ray crystallography, NMR spectroscopy, and electron microscopy. Emphasis on theory and application of these methods for the determination of the three-dimensional structure and dynamics of biological molecules and complexes. Graduate/Undergraduate Equivalency: BIOS 482. Recommended prerequisite(s): BIOS 301, BIOS 352, BIOS 481.

Long Title: TOPICS IN EVOLUTION

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 2

Description: Review and discussion of the literature on current research in evolution. Recommended prerequisite(s): Graduate standing or permission of chair or instructor. Repeatable for Credit.

Long Title: TOPICS IN BEHAVIORAL BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 2

Description: Review and discussion of the literature on current research in animal behavior and evolution. Recommended prerequisite(s): Graduate standing or permission of chair or instructor. Repeatable for Credit.

Long Title: TOPICS IN ECOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 2

Description: Review and discussion of the literature on current research in ecology. Repeatable for Credit.

Long Title: TOPICS IN BIOLOGICAL DIVERSITY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 2

Description: Review and discussion of literature on current research in biological diversity. Instructor Permission Required. Repeatable for Credit.

Long Title: CORE COURSE IN ECOLOGY AND EVOLUTIONARY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: Survey of topics in ecology and evolution taught by all EEB faculty.

Long Title: INTRODUCTION TO RESEARCH

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Research

Credit Hours: 1

Description: Introduction of first-year graduate students to the research programs and laboratories of individual faculty members. Open only to BCB graduate students.

Long Title: FOUNDATIONS OF BIOTECHNOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 1

Description: Graduate level introduction to a wide range of research methods in biosciences and bioengineering. Individual faculty members from the Biosciences will each present practices and techniques for their areas of expertise. A web-based methods database will be constructed, with student involvement, from the library of lectures. Cross-list: BIOE 576.

Long Title: FOUNDATIONS OF BIOTECHNOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 1

Description: Graduate level introduction to a wide range of research methods in biosciences and bioengineering. Individual faculty members from the biosciences and bioengineering will each present practices and techniques for their areas of expertise. A web-based methods database will be constructed, with student involvement, from the library of lectures. Cross-list: BIOE 577.

Long Title: BIOTECHNOLOGY PRACTICUM

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Independent Study

Credit Hours: 1

Description: This couse is part of the NIH Biotechnology Training Program and is limited to program participants. Students will receive exposure and training in cutting edge concepts and technologies.

Long Title: GRADUATE SEMINAR IN BIOCHEMISTRY AND CELL BIOLOGY

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hours: 1

Description: A discussion of selected research topics. Required of all Biochemistry and Cell Biology graduate students. Open only to BCB graduate students. Repeatable for Credit.

Long Title: GRADUATE SEMINAR IN BIOCHEMISTRY AND CELL BIOLOGY

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hours: 1

Description: See BIOS 581. Open only to BCB graduate students. Repeatable for Credit.

Long Title: MOLECULAR INTERACTIONS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 3

Description: Review of literature on current biosciences research. Open only to BCB graduate students.

Long Title: GRADUATE SEMINAR IN ECOLOGY AND EVOLUTIONARY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 1

Description: Faculty and student presentations on current research. Required of all Ecology & Evolutionary Biology graduate students. Repeatable for Credit.

Long Title: GRADUATE SEMINAR/ECOLOGY AND EVOLUTIONARY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 1

Description: Continuation of BIOS 585. Repeatable for Credit.

Long Title: GRADUATE SEMINAR FOR 1ST YEAR GRADUATE STUDENTS IN BIOCHEMISTRY AND CELL BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 3

Description: Preparation and presentation of research proposals. Open only to BCB graduate students.

Long Title: ADVANCED CELL BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 3

Description: Review of literature on current biosciences research, with emphasis on human diseases, their treatment, and drug discovery. Biosciences Group A. Graduate/Undergraduate Equivalency: BIOS 488.

Long Title: COMPUTATIONAL MOLECULAR BIOENGINEERING/BIOPHYSICS

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: This is a course designed for students in computationally-oriented biomedical and bioengineering majors to introduce the principles and methods used for the simulations and modeling of macromolecules of biological interest. Protein conformation and dynamics are emphasized. Empirical energy function and molecular dynamics calculations, as well as other approaches, are described. Specific biological problems are discussed to illustrate the methodology. Cross-list: BIOE 589.

Long Title: SPECIAL TOPICS IN BIOCHEMISTRY AND CELL BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 1

Description: Development of specific topic areas at the graduate level.

Long Title: GRADUATE TEACHING IN ECOLOGY AND EVOLUTIONARY BIOLOGY

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: Supervised instruction in teaching Ecology & Evolutionary Biology. Repeatable for Credit.

Long Title: SEMINAR IN COMPUTATIONAL BIOLOGY

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hours: 1

Description: A discussion of selected research topics in computational biology. Repeatable for Credit.

Long Title: SPECIAL TOPICS IN BIOCHEMISTRY AND CELL BIOLOGY

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hours: 1

Description: Discussion of selected research topics in current plant biology literature. Repeatable for Credit.

Long Title: TRAINING IN THE RESPONSIBLE CONDUCT OF RESEARCH

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Lecture

Credit Hours: 1

Description: This course will consider ethical issues involving human and animal subjects, record keeping, publications, potential conflict of interest, and behavior toward colleagues, research fellows, students, and employees. Cross-list: BIOE 594.

Long Title: GRADUATE TEACHING IN BIOCHEMISTRY AND CELL BIOLOGY

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Independent Study

Credit Hours: 1

Description: Supervised instruction in teaching biochemistry and cell biology. Repeatable for Credit.

Long Title: RESEARCH SEMINAR

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hours: 3

Description: Discussion of individual laboratory research or current topics in particular areas. Repeatable for Credit.

Long Title: RESEARCH SEMINAR

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hours: 3

Description: Continuation of BIOS 611. Repeatable for Credit.

Long Title: THESIS SEMINAR

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 1

Long Title: THESIS SEMINAR

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Research

Credit Hours: 1

Long Title: MECHANICAL AND THERMODYNAMIC PROPERTIES OF BIOMEMBRANES

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: The mechanical properties of membranes influence several biological processes including endocytosis, fusion, signaling an cellular differentiation. this course will cover the theoretical foundations for membrane mechanics, examine experimental methods for measuring membrane material properties, including nanomechanical and optical techniques, and emphasize the importance of membrane mechanics in bioengineering applications. Instructor Permission Required.Cross-list: PHYS 643.

Long Title: GRADUATE LAB RESEARCH I

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Laboratory

Credit Hours: 1 TO 4

Description: Graduate research in Biochemistry and Cell Biology. Designed for short term laboratory projects for first year graduate students. Recommended prerequisite(s): Graduate standing in Biochemistry and Cell Biology. Repeatable for Credit.

Long Title: GRADUATE LAB RESEARCH II

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Laboratory

Credit Hours: 1 TO 4

Description: Graduate research in Biochemistry and Cell Biology. Designed for short term laboratory projects for first year graduate students. Recommended prerequisite(s): Graduate standing in Biochemistry and Cell Biology. Repeatable for Credit.

Long Title: VISITING RESEARCH TRAINEE

Department: Biosciences

Grade Mode: Audit

Course Type: Research

Credit Hours: 0

Long Title: BIOCHEMISTRY & CELL BIOLOGY GRADUATE RESEARCH

Department: Biosciences

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Laboratory

Credit Hours: 1 TO 15

Description:  Repeatable for Credit.

Long Title: EEB GRADUATE RESEARCH

Department: Biosciences

Grade Mode: Standard Letter

Course Type: Research

Credit Hours: 1 TO 15

Description:  Repeatable for Credit.