Course Schedule and Catalog

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): (PHYS 125 AND PHYS 126) OR (PHYS 101 AND PHYS 102) AND CHEM 121 AND CHEM 122 AND MATH 101 AND MATH 102 AND CAAM 211 OR CAAM 210

Description: BIOENGINEERING FUNDAMENTALS ***** Introduction to material, energy, charge and momentum balances in biological systems. Steady-state and transient conservation equations for mass, energy, charge and momentum will be derived and applied using basic mathematical principles, physical laws, stoichiometry, and thermodynamics properties. Required for students intending to major in bioengineering. Offered only in the Fall semester. ***** Prerequisite(s): PHYS 125 and 126 or PHYS 101 and 102, CHEM 121 and 122, MATH 101 and 102, CAAM 211 or 210. ***** Co-requisite(s): MATH 211. ***** Instructor(s): San, Saterbak.

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: BIOTECHNOLOGY AND WORLD HEALTH ***** This course provides an overview of contemporary technological advances to imporve human health. The course opens with an introduction to the epidemiology and physiology of the major human health problems throughout the world. With this introduction, we examine medical technologies to prevent infection, detect cancer and treat heart disease. We discuss legal and ethical issues associated with developing new medical technologies. The course is designed for non-engineering majors.

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Description: SYSTEMS PHYSIOLOGY LAB MODULE ***** Exploration of common biomedical equipment including EEG, ECG, pulmonary function test, etc. Students will explore concepts through computer simulations and data collection and analysis. Enrollment in or completion of BIOE 322 is expected. For students intending to major in Bioengineering. ***** Enrollment limited to 9 per section. ***** Prerequisite(s): BIOE 322 and BIOE 252 ***** Instructor(s): Saterbak

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOE 252

Description: CELLULAR ENGINEERING ***** Introduction to engineering principles and modeling at the cellular level. Topics include cytomechanics, receptor/ligand binding, genetic engineering, enzyme kinetics, and metabolic pathway engineering. ***** Prerequisite(s): BIOE 252 or permission of instructor. ***** Instructor(s): Athanasiou, San

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOS 201 AND MATH 211

Description: FUNDAMENTALS OF SYSTEMS PHYSIOLOGY ***** This course will teach the fundamentals of physiology at the organism, tissue, and cellular levels. Emphasis will be on engineering aspects of physiology. ***** Prerequisite(s): BIOS 201 and MATH 211. ***** Instructor(s): West

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: THERMODYNAMICS ***** This course will be mathematically rigorous coverage of the fundamentals of thermodynamics with applications drawn from contemporary bioengineering problems. Topics covered include thermodynamics of self assembly, the hydrophobic effect, polymer and membrane phase transitions, membrane transport, cell mechanics, electromechanical coupling in biological systems, nonequilibrium thermodynamics, open systems and statistical mechanics. ***** Prerequisite(s): BIOE 252, BIOE 391, BIOE 383 or permission of instructor. Instructor(s): Raphael

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture/Laboratory

Credit Hours: 1

Prerequisite(s): BIOS 211 OR CHEM 214

Description: LAB MODULE IN TISSUE CULTURE ***** Introduction to tissue culture techniques, including cell passage, cell attachment and proliferation assays, and a transfection assay. Sections 1 and 2 are taught during the first half of the semester. Sections 3 and 4 are taught during the second half of the semester. Section sign-up is required by the instructor in Keck 108 during preregistration week. ***** Enrollment limited to 12 per section. ***** Also offered as BIOS 320. ***** Prerequisite(s): BIOS 211 or CHEM 215 or permission of the instructor. ***** Instructor(s): Saterbak

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOE 252

Description: INTRODUCTION TO BIOMECHANICS AND BIOMATERIALS ***** Introduction to the fundamentals of biomechanics including force analysis, mechanics of deformable bodies, stress and strain, multiaxial deformations, and viscoelasticity. Biomechanics of soft and hard tissues. Physical and The focus of this course is on the understanding of chemical properties of biomaterials. Materials covered include both natural and synthetic ones intended to function fundamental issues related to biomechanics of the human body in the biological environment. , reactions of different types of tissue and synthetic material to load and the biomechanics of biomaterial. In examples, the effect of mechanical conditions on the human body function and the effect of tissue property on whole body behavior will be reviewed. ***** Prerequisite(s): BIOE 252, MECH 211, or permission of the instructor. ***** Instructor(s): Liebschner

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: FUNDAMENTALS OF ELECTROPHYSIOLOGY ***** Introduction to cellular electrophysiology. Includes the development of whole-cell models for neurons and muscle (cardiac, skeletal and smooth muscle) cells, based on ion channel currents obtained from whole-cell voltage-clamp experiments. Ion balance equations are developed, as well as, those for chemical signaling agents such as "second messengers." The construction of small neuron circuits are discussed. Volume conductor boundary-value problems frequently encountered in electrophysiology are posed, and solutions obtained based on adequate descriptions of the bioelectric current source and the volume conductor (surrounding tissue) medium. This course provides a basis for the interpretation of macroscopic bioelectric signals such as the electrocardiogram (ECG), electromyogram (EMG) and electroencephalogram (EEG). ***** Also offered as ELEC 381. ***** Prerequisite(s): Consent of instructor ***** Instructor(s): Clark

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Laboratory, Lecture

Credit Hours: 3

Prerequisite(s): MATH 211 AND MATH 212 AND PHYS 126 AND CHEM 122 AND BIOS 201 AND BIOE 252

Description: BIOMEDICAL ENGINEERING INSTRUMENTATION ***** This is an introductory level course on fundamentals of biomedical engineering instrumentation and analysis. Topics include measurement principles; fundamental concepts in electronics including circuit analysis, data acquisition, amplifiers, filters and A/D converters; Fourier analysis; temperature, pressure, and flow measurements in biological systems. Laboratory sections will be offered 2-5pm on M,T,W, TH. ***** Also offered as ELEC 383. ***** Prerequisite(s): MATH 211/212, PHYS 126 or equivalent, CHEM 122, BIOS 201, BIOE 252 ***** Instructor(s): Anvari

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): MATH 211 AND MATH 212 AND PHYS 126 AND BIOS 201

Description: BIOPHOTONICS INSTRUMENTATION AND APPLICATIONS ***** Introduction to fundamentals of biophotonics instrumentation related to coherent light generation, transmission by optical components such as lenses and fibers, and modulation and detection. Interference and polarization concepts and light theories including ray and wave optics will be covered. Biomedical applications in optical sensing and diagnosis will be discussed. ***** Prerequisite(s): MATH 211/212, PHYS 126 or equivalent and BIOS 201 ***** Instructor(s): Drezek

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): CAAM 210 OR CAAM 211

Description: NUMERICAL METHODS & STATISTICS ***** Introduction to numerical approximation techniques and statistical methods with bioengineering applications. Topics include error propagation, Taylor's Series expansions , roots of equations, numerical differentiation and integration techniques for solving ordinary differential equations. Statistical methods for hypothesis testing, analysis of variance, probability and regression analysis are also covered. Matlab and other software will be used for solving equations. ***** Prerequisite(s): MATH 211 or 212 and CAAM 210 or 211 ***** Instructor(s): Grande-Allen

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Research

Credit Hours: 1 TO 5

Description: UNDERGRADUATE RESEARCH ***** Independent investigation of a specific topic or problem in modern bioengineering research under the direction of a selected faculty member. May be repeated for credit. ***** Prerequisite(s): Permission of instructor. ***** Instructor(s): San Repeatable for Credit.

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Independent Study

Credit Hours: 3

Description: INDEPENDENT RESEARCH/INTERNSHIP PROGRAM ***** This independent researcg course offers multi-disciplinary training in the area of celluar engineering within the Departments of Bioengineering and Biochemistry & Cell Biology. Areas of research will include engineering of hard and soft tissue formation, cardiovascular tissue engineering, engineering cell surface interactions regulating movement and metabolic engineering. Students will conduct independent research under the supervision of a faculty mentor.

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): MATH 211 AND MATH 212

Description: BIOSYSTEMS TRANSPORT AND REACTION PROCESSES ***** The principles of reaction kinetics and transport phenomena will be used to quantitatively describe biological systems. Cell biology, physiology, anatomy, and materials science topics will be covered as background for the study of cell membrane transport, receptor-ligand interactions, and normal organ function. Models will be introduced to describe pathological conditions, drug pharmaco-kinetics, and artificial organ designs. ***** Also offered as CENG 420. ***** Prerequisite(s): MATH 211/212 ***** Instructor(s): Mikos

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOE 391

Description: PHARMACEUTICAL ENGINEERING ***** This course will examine how pharmaceutical active agents function in the body and how they are delivered to the body. Topics to be covered include the kinetics of drug absorption and tissue distribution along with the transport phenomena associated with the release bioactive agents. Focus will be placed on mathematical modeling of pharmacokinetic and diffusional processes. ***** Prerequisite(s): BIOE 391 or permission of instructor ***** Instructor(s): Nichol

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 1

Prerequisite(s): CAAM 210 OR CAAM 211

Description: STATISTICS FOR BIOENGINEERING ***** Course covers application of statistics to bioengineering. Topics include descriptive statistics, estimation, hypothesis, testing, ANOVA, and regression. Required for students not taking BIOE 391. ***** Prerequisite(s): CAAM 210 or CAAM 211 ***** Instructor(s): Saterbak

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture/Laboratory

Credit Hours: 4

Prerequisite(s): BIOE 342 AND BIOE 252 AND BIOE 372

Description: ADVANCED BIOENGINEERING LAB AND STATISTICS ***** Laboratory modules include biomaterial synthesis and characterization, systems physiology, ethics, mechanical testing of bone and skin, laser tweezers. Lectures focus on application of statistics in bioengineering. Required for students majoring in bioengineering. ***** Prerequisite(s): BIOE 342, BIOE 252, & BIOE 372 ***** Instructor(s): Saterbak

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Description: TISSUE ENGINEERING LAB MODULE ***** Students conduct a series of tests to synthesize PLLA, characterize PLLA and PLGA, monitor PLLA and PLGA degradation, and assess the viability, attachment, and proliferation of HDF cells on PLLA films. The experiments include many of the basic types of experiments that would be required to do a preliminary investigation of a tissue engineered product. Sections 1 and 2 will be taught during the first half of the semester and sections 3 and 4 will be taught during the second half of the semester. In addition sections 1 and 3 will need to come into lab on 2-3 Fridays and sections 2 and 4 will need to come into lab on 2-3 Saturdays. Section sign-up is required by the instructor in Keck 108 during preregistration week. ***** Enrollment limited to 8. ***** Prerequisites: BIOE 342 ***** Instructor(s): Saterbak

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Description: BIOPROCESSING LAB MODULE ***** Students conduct a series of experiments to observe the growth of E. coli under different conditions, including agar platers, shake flasks, and a small-scale bioreactor. The E. coli has been transformed with a plasmid that produces beta-galactosidase. Some work "off hours" (early evening) is required. Section 1 is taught in the first half of the semester and Sections 2 and 3 will be taught in the second half of the semester. Section sign-up is required by the instructor in Keck 108 during preregistration week. ***** Enrollment limited to four. ***** Prerequisites: BIOE 342 ***** Instructor(s): Saterbak

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Description: MECHANICAL TESTING LAB MODULE ***** Students conduct a series of tests to elucidate the mechanical and material properties of chicken bones, tendons, and skin using the Instron. Students also test biodegradable sutures and materials that have been repaired with sutures. Sections 1 through 4 will be taught in the second half of the semester. Section 5 will be taught in the first half of the semester. Section sign-up is required by the instructor in Keck 108 during the preregistration week. ***** Enrollment limited. ***** Prerequisites: BIOE 372 ***** Instructor(s): Staff

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 1

Description: ADVANCED INSTRUMENTATION LAB MODULE ***** Students design, build and test an instantaneous cardiotachometer as an example of developing the instrumentation for a biomedical instrument or device. ***** Instructor(s): Oden

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: BIOENGINEERING DESIGN I ***** Senior Bioengineering students will design devices in biotechnology or biomedicine. This project-based course covers systematic design processes, engineering economics, FDA requirements, safety, engineering ethics, design failures, research design, intellectual property rights, business planning and marketing. Students will be expected to compile concise documentation and present orally progress of their teams. ***** It is required that students take both parts of this course in the same school year. ***** Prerequisite(s): BIOE 252, BIOE 372, BIOE 383 ***** BIOE 451 and 452 must be taken the same academic year. ***** Instructor(s): Oden

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: BIOENGINEERING DESIGN II ***** Senior Bioengineering students will design devices in biotechnology or biomedicine. This project-based course covers systematic design processes, engineering economics, FDA requirements, safety, engineering ethics, design failures, research design, intellectual property rights, business planning and marketing. Students will be expected to compile consise documentation and present orally progress of their teams. ***** It is required that students take both parts of this course int he same school year. ***** Prerequisite(s): BIOE 451 ***** BIOE 451 and 452 must be taken the same academic year. Instructor(s): Oden

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): MECH 371

Description: FINITE ELEMENT OF METHODS IN FLUID MECHANICS ***** Fundamental concepts of finite element methods in fluid mechanics, including spatial discretization and numerical integration in multidimensions, time-integration, and solution of nonlinear ordinary differential equation systems. Advanced numerical stabilization techniques designed for fluid mechanics problems. Strategies for solution of complex, real-world problems. Topics in large-scale computing, parallel processing, and visualization. ***** Also offered as CEVE 454 and MECH 454. ***** Prerequisite(s): MECH 371 or permission of the instructor. ***** Instructor(s): Tezduyar

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: BIOCHEMICAL ENGINEERING ***** Design, operation, and analysis of processes in the biochemical industries. Topics include enzyme kinetics, cell growth kinetics, energetics, recombinant DNA technology, microbial, tissue and plant cell cultures, bioreactor design and operation, and down stream processing. ***** Also offered as Ceng 460. ***** Instructor(s): San

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOE 372

Description: EXTRACELLULAR MATRIX ***** This course will address the biology, organization, mechanics, and turnover of extracellular matrix. There will be an emphasis on cells and cell-matrix interactions, matrix distributions in connective tissues and organs, techniques for measurement and modeling, changes with growth and aging, and tissue/matrix degradation including enzyme kinetics. ***** Prerequisite(s): BIOE 372 or permission of instructor. ***** Instructor(s): Grande-Allen

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 4

Description: FROM SEQUENCE TO STRUCTURE: AN INTRODUCTION TO COMPUATIONAL BIOLOGY ***** This course is a modern introduction to problems in computational biology spanning sequence to structure. The course has three modules: the first introduces statiscal techniques in sequence analysis; the second covers statistical machine learning techniques for understanding experimental data generated in computational biology; and the third introduces problems in the structure of complex biomolecules. ***** Also offered as STAT 470 and COMP 470.

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Laboratory

Credit Hours: 3

Prerequisite(s): BIOE 372

Description: EXPERIMENTAL TECHNIQUES IN BIOENGINEERING ***** Introduction to experimental techniques used in bioengineering to assess biomaterials and tissues. This course will primarily concentrate on basic concepts of measurement methods, experimental design, signal analysis, and the development of experimental protocols. In laboratory modules focusing on mechanical testing of non-Newtonian materials, parameter extraction out of signal data sets, and electronic circuits. The theoretical concepts covered in class will be implemented hands-on. ***** Prerequisite(s): BIOE 372 or permission of the instructor. ***** Instructor(s): Liebschner

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: COMPUTATIONAL NEUROSCIENCE ***** See description for ELEC 481. ***** Also offered as Elec 481. ***** Instructor(s): Clark

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 4

Description: PHYSIOLOGICAL CONTROL SYSTEMS ***** Nervous system control of biological systems can be represented utilizing techniques common to the field of linear, nonlinear or adaptive control theory. This course begins with a review of the basic aspects of control theory, followed by detailed discussion of the structure of several biological systems including the visual, cardiovascular and pulmonary systems. Specific examples of neural control are developed for each system utilizing modeling and simulation techniques. Parameter sensitivity analysis and parameter estimation techniques are likewise brought to bear on some of these models to achieve good least-squares fits to experimental data. ***** Also offered as ELEC 482. ***** Instructor(s): Clark

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: FUNDAMENTALS OF MEDICAL IMAGING I ***** The course will introduce basic medical imaging modalities, such as x-ray, CT, and MRI, used to identify the anatomy of human organs, as well as other modalities, such as PET, SPECT, fMRI, and MEG, specifically developed to localize brain function. The course includes visits to clinical sites. ***** Also offered as ELEC 485 and COMP 485. ***** Prerequisite(s): Permission of the instrcutor ***** Instructor(s): Mawlawi

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: FUNDAMENTALS OF MEDICAL IMAGING II ***** This course is directed towards graduate and senior undergraduate students interested in acquiring an in depth knowledge of Positron Emission Tomography (PET). The course will focus on PET physical principles, image formation, and processing. The course will also cover the various correction techniques used to quantify PET images as well as lay the foundations for understanding tracer kinetic modeling. A field trip to MD Anderson's PET facility will be organized to provide the students with hands on experience of PET imaging and data analysis. The use of PET imaging in various medical applications will also be covered. ***** Also offered as ELEC 486 and COMP 486. ***** Instructor(s): Mawlawi

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Independent Study

Credit Hours: 3

Prerequisite(s): BIOE 322 AND BIOE 332

Description: SENSORY NEUROENGINEERING I ***** This course will explore how bioengineering techniques and principles are applied to sensory systems, with a focus on the auditory, vestibular, and retinal systems. The interaction between the electrical, mechanical and optical aspects of these systems, and ways to modulate these interactions, will be explored. Design and current technologies used as auditory and visual prosthetics will be covered. ***** Enrollment limited to 15. ***** Prerequisites: BIOE 322, BIOE 332, or permission of instructor. ***** Instructor(s): Raphael

Department: Bioengineering

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Research

Credit Hours: 1 TO 15

Description: GRADUATE RESEARCH ***** Instructor(s): Staff Repeatable for Credit.

Long Title: OPTICAL IMAGING

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: OPTICAL IMAGING ***** This course includes a theoretical portion which will introduce the fundamentals of optical imaging of neural activity, present the devices that are employed, and review applications and discuss their results. In addition, in a practical part, students will design, set up, and perform simple in vitro experiments to gain practical experience with this exciting and powerful technology. ***** Course meets in S744, Vivian Smith Res. Bldg.,Baylor College of Medicine ***** Instructor(s): Saggau

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: BIOSYSTEMS TRANSPORT PHENOMENA ***** The principles of transport phenomena will be used to quantitatively describe biological systems. ***** Prerequisite(s): Permission of the instructor ***** Instructor(s): Deem

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: GENE THERAPY COURSE ***** This course will review the principles and strategies underlying gene therapy approaches in animal models and human beings. The current methods for gene delivery to cells ex vivo and in vivo will be discussed along with current cutting-edge approaches for improving the specificity and persistence of gene expression. The course will also cover current disease applications of gene therapy and the strategies taken to produce therapeutic results. Regulatory issues concerning biomaterials will also be addressed. ***** Prerequisites: CHEM 212, BIOS 201 ***** Limited to Graduate Students. ***** Instructor(s): Barry

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: BIOMATERIALS ENGINEERING ***** Emphasis will be placed on issues regarding design and synthesis of materials to achieve specific properties and biocompatibility. An overview of significant biomaterials application will be given, including topics such as opthalmic biomaterials, orthopedic applications, cardiovascular biomaterials, and drug delivery systems. Regulatory issues concerning biomaterials will also be addressed. ***** Prerequisite(s): Organic chemistry and biology ***** Instructor(s): West Repeatable for Credit.

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 1

Description: INTRODUCTION TO BIOENGINEERING ***** Seminar/tutorial introducing current research in bioengineering and biotechnology to acquaint students with activities of various labs at Rice and the Texas Medical Center. ***** Also offered as CENG 551. ***** Prerequisite(s): Graduate standing or permission of the instructor. ***** Instructor(s): Deem

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): MECH 371 AND MECH 517

Description: FINITE ELEMENT METHODS IN FLUID MECHANICS ***** Graduate version of BIOE 454. Additional work requried. ***** Prerequisite(s): MECH 371 and MECH 517 or permission of the instructor. ***** Instructor(s): Tezduyar

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: FUNDAMENTALS OF SYSTEMS PHYSIOLOGY ***** This course will teach the fundamentals of physiology at the organism, tissue, and cellular levels. Emphasis will be on engineering aspects of physiology. ***** Prerequisite(s): BIOS 201, MATH 212 ***** Instructor(s): Drezek

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): BIOE 372

Description: CONTINUUM BIOMECHANICS ***** Biomechanics models at an advanced mathematical level. Selected topics in tensor analysis, continuum biomechanics, mixture theories, elasticity, and viscoelasticity. Applications in soft and hard tissues. ***** Prerequisite(s): BIOE 372 or permission of the instructor. ***** Instructor(s): Athanasiou

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 1

Description: FOUNDATIONS OF BIOTECHNOLOGY ***** Graduate level introduction to a wide range of research methods in biosciences and bioengineering. Individual faculty memebrs from the Biosciences and Bioengineering will each present practices and techniques for their areas of expertise. A web-based methods database will be constructed, with student involvement, from the library of lectures. ***** Also offered as BIOS 576.

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 1

Description: FOUNDATIONS OF BIOTECHNOLOGY ***** Graduate level introduction to a wide range of research methods in biosciences and bioengineering. Individual faculty members from the biosciences and bioengineering will each present practices and techniques for their areas of expertise. A web-based methods database will be constructed, with student involvement, from the library of lectures. ***** Prerequisite(s): Graduate students only. ***** Also offered as BIOS 577. ***** Instructor(s): Cates

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): ELEC 481 AND ELEC 482 AND ELEC 507

Description: CARIOVASCULAR DYNAMICS ***** Analysis of properties and functions of the cardiovascular system. Includes detailed study of cardiac electrophysiology, ventricular mechanics, arterial hemodynamics, coronary and cerebral circulations, heart rate control, and imaging methods for determining ventricular volume and output flow, as well as therapeutic devices and computer-controlled drug delivery systems with their mathematical models. Internship project with engineer or life scientist working in the Texas Medical Center required. Not offered every year. ***** Also offered as ELEC 481. ***** Prerequisite(s): ELEC 481, 482, and 507 or equivalent. ***** Instructor(s): Clark. Repeatable for Credit.

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: LASERS IN MEDICINE AND BIOENGINEERING ***** This course will provide an overview of various types of interactions between lasers and biological tissues. Methods of optical properties measurements, mathematical modeling of light propagation, and selected therapeutic applications of lasers will be addressed. Optically based diagnostic procedures, including absorption and scattering-based techniques, will be introduced. Physics of optical tweezers and their applications in biomedical sciences will be discussed. ***** Prerequisite(s): Differential Equations, Introductory Physics, and Engineering Computation ***** Instructor(s): Anvari Repeatable for Credit.

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: COMPUTATIONAL MOLECULAR BIOENGINEERING ***** This is a course designed for students in computationally-oriented biomedical and bioengineering majors to introduce the principles and methods used for the simulations and modeling of macromolecules of biological interest. Protein conformation and dynamics are emphasized. Empirical energy function and molecular dynamics calculations are described. Specific biological problems are discussed to illustrate the methodology. Classic examples such as the cooperative mechanism of hemoglobin and more frontier topics such as the motional properties of molecular motors and ion channels as well as results derived from the current literature are covered. ***** Suggested Prerequisite(s): MATH 212, BIOS 301, BIOE 332 ***** Also offered as BIOS 589. ***** Instructor(s): Ma

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Independent Study

Credit Hours: 3

Description: SENSORY NEUROENGINEERING I ***** This course will explore how bioengineering techniques and principles are applied to sensory systems, with a focus on the auditory, vestibular, and retinal systems. The interaction between the electrical, mechanical and optical aspects of these systems, and ways to modulate these interactions, will be explored. Design and current technologies used as auditory and visual prosthetics will be covered. ***** Instructor(s): Raphael

Department: Bioengineering

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Lecture

Credit Hours: 1

Description: TRAINING IN THE RESPONSIBLE CONDUCT OF RESEARCH ***** This course will consider ethical issues involving human and animal subjects, record keeping, publications, potential conflict of interest, and behavior toward colleagues, research fellows, students, and employees. ***** Also offered as BIOS 594. ***** Enrollment is limited to 40. ***** GRADUATE STUDENTS ONLY. ***** Instructor(s): Staff

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Prerequisite(s): CENG 611 OR BIOE 589 OR BIOS 589 OR CHEM 520 OR PHYS 526

Description: METHODS OF MOLECULAR SIMULATION ***** Modern simulation techniques for classical atomistic systems. Review of statistical mechanical systems. Monte Carlo and molecular dynamics simulation techniques. Extensions of the basic methods to various ensembles. Applications to simulations of large molecules such as proteins. Advanced techniques for simulation of complex systems, including constraint satisfaction, cluster moves, biased sampling, and random energy models. ***** Prerequisite(s): CENG 611 or BIOE/BIOS 589 or CHEM 520 or PHYS 526 or permission of instructor. ***** Instructor(s): Deem

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: TISSUE ENGINEERING ***** Study of cell-cell interactions and the role of the extracellular matrix in the structure and function of normal and pathological tissues. Includes strategies to regenerate metabolic organs and repair structural tissues, as well as cell-based therapies to deliver proteins and other therapeutic drugs, with emphasis on issues related to cell and tissue transplantation such as substrate properties, angiogenesis, growth stimulation, cell differentiation, and immunoprotection. ***** Also offered as CENG 620. ***** Instructor(s): Mikos

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: PHARMACEUTICAL ENGINEERING ***** This course will examine how pharmaceutical active agents function in the body and how they are delivered to the body. Topics to be covered include the kinetics of drug absorption and tissue distribution along with the transport phenomena associated with the release bioactive agents. Focus will be placed on mathematical modeling of pharmacokinetic and diffusional processes. ***** Graduate version of BIOE 425. ***** Instructor(s): Nichol

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: ADVANCED COMPUTATIONAL MECHANICS ***** Advanced topics in computational mechanics with emphasis on finite element methods and fluid mechanics. Stablilized formulations. Fluid-particle and fluid-structure interactions and free-surface and two-fluid flows. Inter-face tracking and interface-capturing techniques, space-time formulations, and mesh update methods. Enhanced discretization and solution techniques. Itertive solution methdos, matrix-free computations, and advanced preconditioning techniques. ***** Also offerd as MECH 654 and CEVE 654 ***** Prerequisite(s): MECH 554 or permission of instructor ***** Instructor(s): Tezduyar

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: FUNDAMENTALS OF MEDICAL IMAGING ***** The course will introduce basic medical imaging modalities, such as x-ray, CT, and MRI, used to identify the anatomy of human organs, as well as other modalties, such as PET, SPECT, fMRI, and MEG, specifically developed to localize brain function. The course includes visits to clinical sites. ***** Also offered as ELEC 685 and COMP 685.

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture

Credit Hours: 3

Description: SPECIAL TOPICS COURSE: INTRODUCTION TO BIOMECHANICS AND BIOENGINEERING ***** Introduction to the fundamentals of Biomechanics including force analysis, mechanics of deformable bodies, stress and strain, multiaxial deformation, and viscoelasticity. Biomechanics of soft and hard tissues. Physcial and chemical properties of biomaterials. Materials covered include both natural and synthetic ones intended to function in the biological environment. ***** Instructor(s): Liebschner

Long Title: ADVANCED MODELING OF TISSUE MICROMECHANICS

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Lecture/Laboratory

Credit Hours: 3

Prerequisite(s): BIOE 595

Description: ADVANCED MODELING OF TISSUE MICROMECHANICS ***** Continuation of MECH 595/BIOE 595 with emphasis on advanced modeling the micromechanics of biological tissues. Independent study and seminar/discussion course. Data from experiments will be used to refine the predictions of mathematical models. Designed for juniors, seniors, and graduate students. Laboratory work performed at Baylor College of Medicine and Computer work at Rice University. ***** Prerequisite(s): BIOE 595 ***** Instructor(s): Boriek

Department: Bioengineering

Grade Mode: Satisfactory/Unsatisfactory

Course Type: Seminar

Credit Hours: 1

Description: GRADUATE SEMINAR ***** Instructor(s): Staff Repeatable for Credit.

Department: Bioengineering

Grade Mode: Standard Letter

Course Type: Seminar

Credit Hours: 1

Description: GRADUATE SEMINAR ***** Instructor(s): Drezek Repeatable for Credit.